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Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro.
Published 2016“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”
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Klf5 expression is down-regulated in the ruptured human and experimental AAA.
Published 2020Subjects: -
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The correlation of the mitochondrial dynamics–related genes with Klf5 in mouse VSMCs.
Published 2020Subjects: -
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Dexamethasone decreases CRTC1 and CRTC2 nuclear localization.
Published 2016“…Dex increased (D) nuclear SIK1 protein (p = 0.005) with no detectable difference in cytosolic protein. n = 3-7/treatment from 3–5 experiments. (E) Representative western blots for cytosolic and nuclear CRTC1, CRTC2, SIK, and CnA proteins are shown; controls for the nuclear (Histone) and cytosolic (GAPDH) fractions are also shown. …”
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Dexamethasone decreases PGC-1α protein expression and transcription.
Published 2016“…<p>(A) Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased PGC-1α protein expression (p = 0.01). n = 3/treatment from 3 experiments. …”
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