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Gene ontology biological processes overrepresented among genes exhibiting decreased expression in human psoriasis.
Published 2011“…<p>A total of 3540 transcripts were identified as significantly decreased in psoriatic plaques obtained from human patients relative to normal skin obtained from control subjects (FDR-adjusted P<0.05 and log<sub>2</sub>-transformed fold-change less than -0.50). …”
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1173
TGF-β-mediated EMT decreases Dlg5 expression.
Published 2012“…The cells were immunostained with anti-Dlg5 or anti-E-cadherin antibody. The scale bar indicates 10 µm. …”
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1174
Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol
Published 2013“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”
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1175
Interactions between E1A and PKA are required for full HAdV-5 progeny production.
Published 2016“…<p>A549 cells were treated with control siRNA or siRNA specific for PKA subunits and infected with either WT HAdV-5 or a virus encoding E1A unable to bind PKA (Δ4–25). …”
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