Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach - Fig 9 by Sneha P. (3926957)

Effect of parasitism and PDV injection on triglyceride concentration and lipid metabolism-related gene expression in FAW larvae. by Xian Li (201841)

Effect of parasitism and PDV injection on lipid droplet size in the fat body of FAW larvae. by Xian Li (201841)

RKIP inhibits breast cancer metastasis by decreasing MMP13 expression by targeting the Erk2 signaling pathway. by Ila Datar (433874)

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Spontaneous beating rates in mESC-CMs. by Yukihiro Saito (797587)

Onset-treatment with HBPDS decreases the mRNA expression of inflammatory mediators in the spinal cord from EAE mice. by Jong Hee Choi (804357)

“…The mRNA expression levels of TNF-a (A), IL-1b (B), IL–6 (C), iNOS (D), MCP–1 (E), MIP–1α (F), and RANTES (G) were significantly decreased in the spinal cord of EAE mice by onset-treatment with HBPDS (30% ethanol extracted). …”

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology by Laurence J. Howe (5579186)

“…Where evidence was found of genetic overlap, we used bidirectional Mendelian randomization (MR) to test the hypothesis that genetic liability to nsCL/P is causally related to implicated facial phenotypes. Across 5,804 individuals of European ancestry from two studies, we found strong evidence, using PRS, of genetic overlap between nsCL/P and philtrum width; a 1 S.D. increase in nsCL/P PRS was associated with a 0.10 mm decrease in philtrum width (95% C.I. 0.054, 0.146; P = 2x10^-5). …”

VEGF overexpression in OU culture increased OU size and altered stem/progenitor cell gene expression. by Christopher R. Schlieve (3179439)

“…(C) Significant increase in Bmi1 and Atoh1 expression and decrease in EphB2 expression was observed in doxycycline-treated VEGF OU compared to controls at 5 days (*p<0.05). …”

CK1δ-specific kinase activity in HT1080 cells is decreased after activation of Chk1. by Joachim Bischof (189845)

Number of trees at the end time resulting from simulation of the optimal control P3 with <i>ω</i>₁ = 1, <i>ω</i>₂ = .5, <i>ω</i>₃ = .1 and <i>u</i>... by Maria C. A. Leite (5586701)

An illustration of the subnetwork containing ADRA2A and TBXA2R. by Noël Malod-Dognin (8677110)

Airway recruitment of IFN-γ-producing CD8⁺ T-cells is decreased in response to <i>p</i>-formaldehyde-fixed or heat-inactivated <i>A. fumigatus</i> conidia. by Steven P. Templeton (224749)

sFlt-1 mutant mice demonstrated increased lysozyme-positive cells per hemicrypt. by Christopher R. Schlieve (3179439)

A photomicrograph of sections of the ovary in different groups [ki67 immunostaining x200]. by Rasha Atta (21608582)

“…<p>A) The control group shows ki67 immunoreaction in the granulosa (G) cells of different ovarian follicles, the unilaminar primary (UF), the multilaminar primary (MF), and the secondary (SF) follicle. …”

HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model - Fig 3 by Thaiz F. Borin (4107397)