MicroRNA-520b Inhibits Growth of Hepatoma Cells by Targeting MEKK2 and Cyclin D1 by Weiying Zhang (185279)

“…In addition, miR-520b significantly decreased the phosphorylation levels of c-Jun N-terminal kinase (p-JNK, a downstream effector of MEKK2) or retinoblastoma (p-Rb, a downstream effector of cyclin D1). …”

Potential of hydrogen (pH) differentially modulates cadmium stress response in abscisic acid-deficient sitiens tomato mutant by Georgia Bertoni Pompeu (7141529)

“…Moreover, sit shoot grown at pH 5 showed decreased activities of superoxide dismutase (SOD), Mn-SOD II and Cu/Zn-SOD V, in 0 and 50 ?…”

DG granule neuron number, volume, and density estimations in P14 rat hippocampus upon prenatal nicotine exposure and postnatal maternal separation. by Hong Wang (13528)

“…<p>Compared to CTL, granule cell numbers of MD and NIC+MD but not NIC groups were significantly decreased (MD, 14.1±1.4%, <i>p<0.05</i>; NIC+MD, 15.9±2.0%, <i>p<0.05</i>) (A). …”

IDR-1002 and LL-37 reduced LPS-induced cytokines and chemokine MCP-1 in RAW cells. by Kelli C. Wuerth (4574026)

“…LL-37 also decreased LPS-induced IL-6 (D), TNF-α (E), and MCP-1 (F). …”

Etv2 overexpression induces vascular gene expression and represses muscle gene expression. by Matthew B. Veldman (177124)

“…The numbers in the higher magnification views represent the number of embryos exhibiting normal expression levels. (E) qPCR for muscle genes <i>myod1</i>, <i>myog</i>, <i>myf6</i>, <i>mylpfa</i>, and <i>tnnt3a</i> shows significantly decreased expression 4 h post–heat shock. qPCR was performed on three separate clutches. (**) <i>p</i><0.01, <i>t</i> test versus non–heat shocked control.…”

Increasing <i>G</i>⁽¹⁾ impairs the ability to form connections between activated MCs and GCs. by John Hongyu Meng (14002826)

“…(C) Effective connectivity <i>W</i>^(<i>mm</i>). (D,E,G) as (A,B,C) except for <i>G</i>⁽¹⁾ = 10. …”

Genes and biological processes affected by <i>Scap</i> deletion in the developing lung. by James P. Bridges (560804)

“…The intensity in the red and green color ranges indicates increased versus decreased mRNAs, respectively. Each row represents a single mRNA, and each column represents an average fold change between knockout and control mice at the specified gestational age. …”

TLR4 deficiency diminished glomerular injury in DN. by Jin Ma (335456)

“…<p>WT diabetic mice showed significant glomerular injury including increased kidney to body weight ratio (A), glomerular volume (B), glomerular cellularity (C, week 24), glomerular mesangial matrix (D & E), decreased podocin staining (F) and WT1⁺ podocyte numbers (H & I) compared to non-diabetic WT controls. …”

Robustness of the segmentation algorithm. by N. Ezgi Wood (6519662)

“…Note that the algorithm segments the cells backwards in time, thus time points (i.e. frame numbers) are decreasing. <b>(B)</b> The seeds of 340 cells were perturbed by randomly removing 10–90% of the seed. …”

<i>Oprm1</i>^−/− mice perform better in the signaled nose poke task. by Mary C. Olmstead (345716)

“…<p>Performance on Phase 4 of the signaled nose poke task for mu-opioid receptor knockout mice and their wild-type controls on a HYB (A–D) and BL6 (E–H) backgrounds. A and E: Efficiency ratios (rewards/nose pokes) increased across sessions with <i>Oprm1 ^−/−</i> mice on both genetic backgrounds performing significantly better than wild-type controls. …”

PRC2 components are altered in animal models of diabetes and other endothelial cell types exposed to high glucose. by Michael Anthony Ruiz (726055)

“…<b>A:</b> After 1 month of diabetes, VEGF expression was increased and miR-200b expression was decreased. …”

Change in Allosteric Network Affects Binding Affinities of PDZ Domains: Analysis through Perturbation Response Scanning by Z. Nevin Gerek (174461)

“…One solution to this problem is to explore the dynamics of PDZs, which may provide insights about how intramolecular communication occurs within a single domain. Here, we develop an advancement of perturbation response scanning (PRS) that couples elastic network models with linear response theory (LRT) to predict key residues in allosteric transitions of the two most studied PDZs (PSD-95 PDZ3 domain and hPTP1E PDZ2 domain). …”

Immunofluorescence and immunoblotting for PKBβ/Akt2 and PKBα/Akt1 in VOT-N33 cultured with and without <i>gata3</i> siRNA. by Marta Milo (232638)

“…C–D – Treatment with gata3 siRNA caused a loss of label for both gata3 and PKBβ/Akt2. E–F – In untreated cells PKBα/Akt1 was localized primarily to the nuclei but with siRNA to <i>gata3</i> the label was much higher and localized to the cytoplasm. …”

Data_Sheet_1_Congenital Zika Virus Infection in Immunocompetent Mice Causes Postnatal Growth Impediment and Neurobehavioral Deficits.pdf by Amber M. Paul (815915)

Deciphering Heterogeneity in Pig Genome Assembly Sscrofa9 by Isochore and Isochore-Like Region Analyses by Wenqian Zhang (240091)

“…</p><h3>Principal Findings</h3><p>In this paper, we construct a map of long homogeneous genome regions (LHGRs), i.e., isochores and isochore-like regions, in pigs to provide an intuitive version of GC heterogeneity in each chromosome. …”

Detection of OMVs and EHEC-Hly in lysosomal and mitochondrial fractions of cells treated with EHEC-Hly-containing OMVs. by Martina Bielaszewska (79970)

“…(I–L) Densitometric quantification of OmpA (I, J) and EHEC-Hly (K, L) signals shown in E, F and G, H, respectively, using Quantity One software; * significantly decreased (<i>p</i><0.05) compared to 8 h; ** significantly increased (<i>p</i><0.05) compared to 16 h (unpaired Student's <i>t</i> test). …”

Reproductive Capability Is Associated with Lifespan and Cause of Death in Companion Dogs by Jessica M. Hoffman (403576)

Chronic Mild Stress (CMS) in Mice: Of Anhedonia, ‘Anomalous Anxiolysis’ and Activity by Martin C. Schweizer (267501)

“…</p><h3>Conclusions/Significance</h3><p>The CMS procedure induced some behavioural changes that are compatible with the common expectations, i.e. ‘anhedonic’ behaviour, but in parallel behavioural alterations were observed which would be described as ‘anomalous’ (e.g. decreased anxiety). …”

Image_1_Pest Management in the Postharvest Agricultural Supply Chain Under Climate Change.tiff by Alison R. Gerken (12984695)

“…Tactics susceptible to warming temperature changes in climate showing decreased efficacy include semiochemical-based, behaviorally-based tactics, a subset of insecticides (e.g., pyrethrins and pyrethroids), and those that rely on low temperature (e.g., grain aeration, grain chilling). …”

Implicit emotion regulation in adolescent girls: An exploratory investigation of Hidden Markov Modeling and its neural correlates by James S. Steele (4898566)

“…<div><p>Numerous data demonstrate that distracting emotional stimuli cause behavioral slowing (i.e. emotional conflict) and that behavior dynamically adapts to such distractors. …”