Showing 20,041 - 20,060 results of 132,736 for search '(( a e decrease ) OR ( 5 ((point decrease) OR (((mean decrease) OR (a decrease)))) ))', query time: 1.93s Refine Results
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    <i>Galnt1</i> Is Required for Normal Heart Valve Development and Cardiac Function by E Tian (685836)

    Published 2015
    “…The underlying phenotype is aberrant valve formation caused by increased cell proliferation within the outflow tract cushion of developing hearts, which is first detected at developmental stage E11.5. Developing valves from <i>Galnt1</i> deficient animals displayed reduced levels of the proteases ADAMTS1 and ADAMTS5, decreased cleavage of the proteoglycan versican and increased levels of other extracellular matrix proteins. …”
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    Are Environmental Levels of Nonsteroidal Anti-Inflammatory Drugs a Reason for Concern? Chronic Life-Cycle Effects of Naproxen in Zebrafish by Susana Barros (586042)

    Published 2024
    “…An integration of apical endpoints, i.e., survival, growth, and reproduction, with gonad histopathology and gene transcription (RNA-seq) was performed to provide additional insights into the mode of action (MoA) of NPX. …”
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    Loss of <i>Galnt1</i> causes increased cell proliferation during early valve development. by E Tian (685836)

    Published 2015
    “…Western blotting reveals an increase in phosphorylation of (E) Smad1/5 (BMP) and (F) MAPK (ERK1/2), (G) decreased EGFR in <i>Galnt1</i> null OFT samples relative to wild type at E11.5 (n = 4), and E12.5 (n = 6) while remaining unchanged in E10.5 OFT (n = 3) and in E14.5 AoV (n = 3). …”
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    Fig 2 - by Zhe Xu (127066)

    Published 2023
    Subjects:
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