Image1_Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.JPEG by Dan Sun (140898)

“…Furthermore, the treatment of lidocaine repressed tumor growth of ovarian cancer cells in vivo, in which the miR-382-5p expression was increased while SLC7A11 expression was decreased. …”

Univariate relationship in spatial patterns between nodal entropy and structural brain features within each scan in children. by Tianyuan Lei (19683861)

Optimized TMS performs well in non-human primate species and when compared to RRBS. by Amy Longtin (21409957)

Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1^G93A astrocytes by Veronica Granatiero (10339456)

“…</p> <p><b>Abbreviations:</b> ACM: astrocyte conditioned medium; AKT: AKT serine/threonine kinase; ALS: amyotrophic lateral sclerosis; BrdU: thymidine analog 5-bromo-2’-deoxyuridine; CNS: central nervous system; EIF4EBP1/4EBP1: eukaryotic translation initiation factor 4E binding protein 1; GFAP: glial fibrillary acidic protein; IGF1R: insulin like growth factor 1 receptor; INSR: insulin receptor; iPSA: iPSC-derived astrocytes; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta;MTOR: mechanistic target of rapamycin kinase; NES: nestin; PPK1: 3-phosphoinositide dependent protein kinase 1; PI: propidium iodide; PPP: picropodophyllotoxin; PTEN: phosphatase and tensin homolog; S100B/S100β: S100 calcium binding protein B; SLC1A3/ EAAT1: solute carrier family 1 member 3; SMI-32: antibody to nonphosphorylated NEFH; SOD1: superoxide dismutase 1; TUBB3: tubulin beta 3 class III; ULK1: unc-51 like autophagy activating kinase 1.…”

Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation by Alena V. Savonenko (757228)

“…Specificity of CB2 antibody (H60) was confirmed using J20APPswe/ind mice lacking CB2 receptors. APPswe/PS1ΔE9 mice were used in small animal PET with a CB2-targeting radiotracer, [¹¹C]A836339. …”

AMPK Mediates Glucocorticoids Stress-Induced Downregulation of the Glucocorticoid Receptor in Cultured Rat Prefrontal Cortical Astrocytes by Shi-Ying Yuan (2937669)

“…Glucocorticoid-induced effects were attenuated by glucocorticoid-inducible kinase 1 (SGK1) inhibitor GSK650394, which also inhibited glucocorticoid induced phosphorylation of Forkhead box O3a (FOXO3a). Furthermore, glucocorticoid-induced down-regulation of GR was mimicked by the inhibition of AMPK and abolished by the AMPK activators or the histone deacetylase 5 (HDAC5) inhibitors. …”

<i>In vitro</i> and <i>in vivo</i> tumorigenesis of A172 and U373 cells treated with miR-326 precursor. by Jingxu Zhou (433624)

“…The tumors were measured in two dimensions using a caliper on different days. The volume (mm³) was calculated using the formula V = 0.5* larger diameter *(smaller diameter)². miR-326 overexpression or <i>NOB1</i> shRNA significantly inhibited tumor formation. …”

Inflammatory cells and expression of IL-17, IL-23, IL-22 and IFN-γ before and during treatment with IMQ 5% cream or MAL-PDT. by Cristina Pellegrini (4382356)

“…<p>(A) Number of inflammatory cells increased significantly during the inflammatory phase of IMQ treatment (p<0.01) and the early time point of MAL-PDT treatment, while decreased at the late time point (*p<0.05). …”

Spatial patterns of nodal module overlap (i.e., nodal entropy) for different network analysis strategies and their relationships with the main results. by Tianyuan Lei (19683861)

Effects of metformin on depressive behavior and expression of GR in prefrontal cortex of rat after chronic exposure to CORT. by Shi-Ying Yuan (2937669)

Expression analysis in strain B728a of three FecI-like ECF σ factor genes (<i>ecf5</i>, <i>ecf7</i>, and <i>ecf6</i>) and associated putative iron-responsive genes in low and high... by Poulami Basu Thakur (389600)

DRLE prevented ISO-induced elevation of CPK, LDH, GOT, and TNF-α, and elevated serum NO level. by Lung-Shuo Wang (3391244)

Field evaluation of orange rust reaction and genotyping of molecular markers for the <i>G1</i> gene in a nuclear collection of 299 sugarcane accessions. by Gleicy Kelly Oliveira (19259604)

The oxygen level (kPa) for 50 and 100% habitat loss for each species and season under a doubling of atmospheric CO₂. by Emily Slesinger (6837740)

MERGER AND ACQUISITION IN E-COMMERCE SECTOR by Khushboo Sagar (582440)

A Membrane-bound eIF2 Alpha Kinase Located in Endosomes Is Regulated by Heme and Controls Differentiation and ROS Levels in <i>Trypanosoma cruzi</i> by Leonardo da Silva Augusto (195970)

“…The augmented level of hydrogen peroxide occurs as a consequence of increased superoxide dismutase activity and decreased peroxide activity. …”

Table_1_Paradoxical Effect of LTB4 on the Regulation of Stress-Induced Corticosterone Production.DOC by Gisele A. Locachevic (6591545)

“…Recently, we showed that LTB₄ production by the 5-lipoxygenase (5-LO) pathway regulates IL-1β and PGE₂ release, reducing tissue damage in a model of sterile inflammation. …”

Data_Sheet_1_Paradoxical Effect of LTB4 on the Regulation of Stress-Induced Corticosterone Production.PDF by Gisele A. Locachevic (6591545)

“…Recently, we showed that LTB₄ production by the 5-lipoxygenase (5-LO) pathway regulates IL-1β and PGE₂ release, reducing tissue damage in a model of sterile inflammation. …”

Previdência e Taxa de Juros no Brasil by Brian Bolarinwa Ogundairo (12687360)

Confident Identification of Citrullination and Carbamylation Assisted by Peptide Retention Time Prediction by Carina Villacrés (10063684)