Impact of K16A and K28A mutation on the structure and dynamics of amyloid-β₄₂ peptide in Alzheimer’s disease: Key insights from molecular dynamics simulations<sup>†</sup... by Suniba Shuaib (3825727)

“…The molecular dynamics simulations highlighted that K16A and K28A mutation in the aggregation-prone region, <i>i.e.…”

The complete inventory of the endogenously GFP-tagged <i>C</i>. <i>elegans</i> H2B knock-in embryos during metaphase at the one-cell stage. by Ruixue Zhao (2744689)

Linear mixed effects modeling parameter estimates of IgG antibodies to SARS-CoV-2 spike (full length spike, S) and neutralizing antibodies in nursing home residents—Georgia, Decemb... by Zeshan A. Chisty (18388200)

SIRT3 deletion aggravated pathological development of cardiac remodeling induced by TAC. by Ling-Xin Liu (18387955)

RNAi of the electron transport chain in glutamate neurons extends life span in male <i>Drosophila</i>. by Jessie E. Landis (16378731)

RNAi of electron transport chain components in glutamate neurons is sufficient for female life span extension in <i>Drosophila</i>. by Jessie E. Landis (16378731)

PAR-2 deficiency exacerbates the body temperature during IgE-dependent and IgE-independent anaphylaxis. by Maho Nakazawa (18405297)

“…<p>(A) Decrease in body temperature during IgE-dependent anaphylaxis in WT and PAR-2 KO mice (n = 5 each). …”

RAD-51 focus accumulation is delayed in aged unmated <i>rad-54</i> mutant germlines. by Erik Toraason (5724689)

Overexpression of miR-99a or rapamycin treatment inhibited insulin-induced PKM2 and HIF-1α expression, and glucose consumption and lactate production. by Wei Li (7081)

“…Data were presented by mean±SE (n = 3). The data were analyzed by ANOVA. * and **, indicate significant decrease compared to the control (p<0.05 and p<0.01); ^# and ^##, indicate significant decrease compared to miR-SCR and insulin treatment (p<0.05 and p<0.01). …”

Fig 2 - by Calvin P. Philp (12095878)

Proteomic Comparison of 3D and 2D Glioma Models Reveals Increased HLA‑E Expression in 3D Models is Associated with Resistance to NK Cell-Mediated Cytotoxicity by Weiqi He (698658)

“…The resistance of the 3D-cultured tumor cells to NK cell lysis was mediated by the HLA-E/NKG2A interaction because the administration of antibodies that block either HLA-E or NKG2A completely eliminated this resistance and significantly decreased tumor formation. …”

Proteomic Comparison of 3D and 2D Glioma Models Reveals Increased HLA‑E Expression in 3D Models is Associated with Resistance to NK Cell-Mediated Cytotoxicity by Weiqi He (698658)

“…The resistance of the 3D-cultured tumor cells to NK cell lysis was mediated by the HLA-E/NKG2A interaction because the administration of antibodies that block either HLA-E or NKG2A completely eliminated this resistance and significantly decreased tumor formation. …”

Proteomic Comparison of 3D and 2D Glioma Models Reveals Increased HLA‑E Expression in 3D Models is Associated with Resistance to NK Cell-Mediated Cytotoxicity by Weiqi He (698658)

“…The resistance of the 3D-cultured tumor cells to NK cell lysis was mediated by the HLA-E/NKG2A interaction because the administration of antibodies that block either HLA-E or NKG2A completely eliminated this resistance and significantly decreased tumor formation. …”

The Catalytic Subunit of the System L1 Amino Acid Transporter (<i>Slc7a5</i>) Facilitates Nutrient Signalling in Mouse Skeletal Muscle by Nadège Poncet (527942)

“…Thus, SLC7A5 modulates LNAA-dependent muscle mTOR-S6K signalling in mice, although it appears non-essential (or is sufficiently compensated by <i>e.g</i>. …”

High Light Yield of Sr₈(Si₄O₁₂)Cl₈:Eu²⁺ under X‑ray Excitation and Its Temperature-Dependent Luminescence Characteristics by Chunmeng Liu (1435927)

“…It is found that with increases in temperature, lattice expansion takes place without significant distortion of the coordination around Eu²⁺. As a result, the crystal field splitting of the Eu²⁺ 5d state decreases. …”

High Light Yield of Sr₈(Si₄O₁₂)Cl₈:Eu²⁺ under X‑ray Excitation and Its Temperature-Dependent Luminescence Characteristics by Chunmeng Liu (1435927)

“…It is found that with increases in temperature, lattice expansion takes place without significant distortion of the coordination around Eu²⁺. As a result, the crystal field splitting of the Eu²⁺ 5d state decreases. …”

A Novel PROTAC G9a/GLP Degrader that Inhibits, Similar to G9a siRNA, the Migration of MCF‑7 Breast-Cancer Cells without Affecting Proliferation by Anirban Mukherjee (103177)

Lateral view of a reconstructed right hemimandible showing the volumes of interest. by Natsuko Hichijo (752937)

Lateral (3-A) and medial (3-B) views of the cortical mineralization. by Natsuko Hichijo (752937)

gcn5-F221A can impart a graded phenotype as detected by histidine starvation assays. by Amanda M. Lanza (168454)

“…Increasing the expression level of <i>gcn5-F221A</i> (through progressively stronger promoters) results in a decrease in growth rate approaching the value of the knockout strain. …”