Table_5_Anti-breast Cancer Enhancement of a Polysaccharide From Spore of Ganoderma lucidum With Paclitaxel: Suppression on Tumor Metabolism With Gut Microbiota Reshaping.xlsx by Jiyan Su (5218232)

“…Flowcytometry analysis revealed that the combination treatment recovered the exhausted tumor infiltration lymphocytes (TILs) via inhibiting the expressions of immune checkpoints (PD-1 and Tim-3), while PTX alone evidently increased that of CTLA-4. 16S rRNA sequencing revealed a restoration by the combination treatment on gut microbiota dysbiosis induced by PTX, especially that Bacteroides, Ruminococcus, and other 5 genera were significantly enriched while the cancer-risk genera, Desulfovibrio and Odoribacter, were decreased. …”

Table_5_Anti-breast Cancer Enhancement of a Polysaccharide From Spore of Ganoderma lucidum With Paclitaxel: Suppression on Tumor Metabolism With Gut Microbiota Reshaping.xlsx by Jiyan Su (5218232)

“…Flowcytometry analysis revealed that the combination treatment recovered the exhausted tumor infiltration lymphocytes (TILs) via inhibiting the expressions of immune checkpoints (PD-1 and Tim-3), while PTX alone evidently increased that of CTLA-4. 16S rRNA sequencing revealed a restoration by the combination treatment on gut microbiota dysbiosis induced by PTX, especially that Bacteroides, Ruminococcus, and other 5 genera were significantly enriched while the cancer-risk genera, Desulfovibrio and Odoribacter, were decreased. …”

The N-terminus of E1A, but not CR3 requires hPaf1 for efficient transcriptional activation. by Gregory J. Fonseca (421739)

“…Cells were then transfected with a constitutive β-galactosidase reporter, a Gal4 responsive luciferase reporter and a vector expressing the Gal4 DBD alone, Gal4 DBD fused to the N-terminus of E1A, or Gal4 DBD fused to E1A CR3. …”

Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer’s Disease by Yijun Pan (1369074)

“…The small intestines of APP/PS1 mice exhibited a significant 2.3-fold increase in multidrug resistance-associated protein 2 (Mrp2), a 1.9-fold decrease in monocarboxylate transporter 1 (Mct1), and a 3.6-fold increase in UDP-glucuronosyltransferase (Ugt) 2b5 relative to those from WT mice based on QTAP analysis. …”

Image_5_Selective Histone Deacetylase 6 Inhibition Normalizes B Cell Activation and Germinal Center Formation in a Model of Systemic Lupus Erythematosus.jpg by Jingjing Ren (146874)

Depletion of DOM-A, but not DOM-B affects s-LN_vs maintenance and PDF accumulation. by Zhenxing Liu (399809)

“…Cell number of sLN_vs (marked as square brackets), PDF, PER and TIM levels in sLN_vs were decreased in <i>dom</i> and <i>domA</i> downregulation flies brains (Top right and bottom left panels), while only affected PER and TIM levels in <i>domB</i> downregulation flies (Bottom right panel). …”

Extracellular Matrix degradation pathways are enhanced by acidosis in M.tb infection. by Ashley M. Whittington (16510641)

Endogenous BDNF and TrkB levels in retina and SC at various time points after ONC. by Eline Dekeyster (825249)

“…(D) Collicular TrkB-FL and TrkB-T1 levels follow a very similar increase-decrease pattern after ONC induction, with the turning point situated around 3 d post-ONC. …”

Image5_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin dose-dependently reduced biomarkers of liver function (AST, ALT, bilirubin), inflammation (cells foci), and fibrosis (PSR, SHG), as well as decreasing the mRNA and protein expression of several key inflammation and fibrosis biomarkers (e.g., IL6, TGFβ3, SNAI2, collagen). …”

Presentation_1_Taoren Honghua Drug Attenuates Atherosclerosis and Plays an Anti-Inflammatory Role in ApoE Knock-Out Mice and RAW264.7 Cells.pptx by Yiru Wang (1686439)

“…In RAW264.7 cells, groups with LPS plus Taoren Honghua drug had lower IL-6 and TNF-α, but higher IL-10 than LPS group, as revealed by PCR or ELISA methods. A decrease of total or phosphorylated ERK1/2, JNK, p38, ERK5, STAT3, and AKT were detected, so was the translocation of NF-κB p65 from nuclear to cytoplasm. …”

Recombinant <i>T</i>. <i>cruzi</i> Tcj2 was expressed in <i>E</i>. <i>coli</i> and purified. by Leroy Versteeg (4248760)

Long non-coding RNA Opa interacting protein 5-antisense RNA 1 binds to micorRNA-34a to upregulate oncogenic PD-L1 in non-small cell lung cancer by Xinwei Qiao (488240)

“…In addition, inhibition of OIP5-AS1 and overexpression of miR-34a decreased the expression levels of PD-L1, and miR-34a significantly blocked the role of overexpression of OIP5-AS1. …”

Magnification for the global synchronization and information flow capacity properties of Fig 1. by Chris G. Antonopoulos (528861)

Influences of Surface Substitutional Ti Atom on Hydrogen Adsorption, Dissociation, and Diffusion Behaviors on the α‑U(001) Surface by Peng Shi (132534)

“…However, the diffusion of the dissociated hydrogen atoms is dramatically changed after introduction of a surface substitutional Ti atom. The into-bulk penetration of a hydrogen atom through a defect-free surface is endothermic and needs to overcome an energy barrier of 0.8–0.9 eV. …”

Molecular Insight into the Growth of Hydrogen and Methane Binary Hydrates by Zhengcai Zhang (2235856)

“…Moreover, with increasing temperature, the occupancy of 5¹² and 5¹²6⁴ cages by H₂ decreases, and inversely, the occupancy of cages by CH₄ increases when the temperature is above 240 K. …”

Effect of HCQ on cytokines after a 12-hour stimulation with 8μg/mL HPV (human papilloma virus) peptide pool. by Monika M. Kowatsch (11722292)

Results for the global synchronization and information flow capacity properties for the <i>C.elegans</i> and averaged human BDNs. by Chris G. Antonopoulos (528861)

Electrophoresis of PCR products of X and pre-core regions of HBV genome extracted from serum samples of pregnant women on 2% agarose gel. by Reza Taherkhani (2839067)

Subjects:

Alignment of the amino acid sequences (109–154 aa) of X protein (1698–1838 bp nucleotide sequence) isolated from pregnant women (GenBank accession Nos. OK490617 and OK490618) and t... by Reza Taherkhani (2839067)

Subjects:

Neighbor-joining phylogenetic tree based on ∼380 bp nucleotide sequence (∼270–670 bp of the complete reference genome) of S region of HBV isolates (green mark) from the serum sampl... by Reza Taherkhani (2839067)

Subjects: