Mild hyperthermia treatment enhances particle inflow and localization in breast tumor models. by Dickson K. Kirui (523816)

“…<p>A) SEM micrograph of porous MSVs (1000×400 nm) that allow therapeutic loading; B, C) Time-lapse quantification analyses of fluorescently-labeled MSVs in tumor vasculature showing increased initial and total number MSVs in tumors receiving MHT treatment versus control groups. 5-fold enhancement was observed in SUM159 and 3-fold for MCF7; D) Representative time-lapse images from videos acquired over 60 min, showed decreased number of MSVs with time and adherent particles shown after 60 min. …”

3-Cl-AHPC mediated expression of microRNA targets in pancreatic cancer cells. by Lulu Farhana (411956)

“…<p>(A and B) Reduced expression of mRNA by SYBR-green RT-PCR; (C and E) decreased proteins levels were demonstrated by Western blots analysis. …”

Secondary challenge experiments using the basic and extended models. by David M. Vickers (260122)

“…<p>Re-exposure was modeled by an instantaneous inflow of EBs at each of the above-described times using a multiple of the initial infectious dose, 10×<i>E</i>(0) for both the basic model (A), and the extended model (B). …”

The effects of PQ treatment on <i>in vivo</i> mitochondrial metabolism. by Michael P. Siegel (195229)

“…The ratio of ATP produced per O₂ consumed (P/O ratio) is significantly decreased in a dose-dependent manner with PQ treatment (E). …”

Assessing Antibody Specificity. by Jocelyn M. Wessels (337687)

“…<p>Mouse brain sections were stained by immunohistochemistry with anti-BDNF (A) or Ntrk2 (D) antibodies as positive controls, or with antibody which had been pre-incubated with human recombinant BDNF (B) or Ntrk2 (E) protein, or with normal goat serum as a negative control (C, F). …”

Drawings of the present and future by children in lower Kapuas, West Kalimantan. by Anne-Sophie Pellier (455772)

“…<p>Both the drawings represent respectively the present (A) and future conditions (B) of the forest and animal wildlife. …”

Cardiomyocyte proliferation unaltered at P7 in α<i>MHC-Cre/Foxm1^fl/fl</i> mice. by Craig Bolte (299486)

“…Mice homozygous for the <i>Foxm1^fl/fl</i> allele (in which LoxP sites flank exons 4 through 7 of the <i>Foxm1</i> gene) were mated to mice expressing <i>αMHC-Cre</i> to generate mice with a conditional deletion of <i>Foxm1</i> from cardiomyocytes (<i>αMHC-Cre/Foxm1^fl/fl</i>) (A). …”

DATA ALL PARTICIPANTS.xlsx by Angela Van Sickle (20441450)

“…An additional purpose was to investigate the same parameters using a 5 mL swallow of water. Participants were divided into three groups: young adults (n = 65,= 22.8 years), middle-aged adults (n = 62,= 53.2 years), older adults (n = 65,= 81.5 years). …”

left ventricular echocardiographic representative images. by Miao Wu (338806)

“…According to the curve of mitral diastolic flow, peak velocity at early diastole (E), peak velocity at late diastole (A) and E/A ratio were measured.…”

Supplementary material for cardiac responses to environmental heat exposure in young and older adults.docx by Josh Foster (21527189)

“…In both climates and in both age groups, heat stress <i>a)</i> increased cardiac output by ~0.7 ± 0.8 L/min, <i>b)</i> decreased stroke volume by ~7 <a href="" target="_blank">± </a>10 mL and <i>c)</i> augmented diastolic function through increased atrial contribution to filling by 5 ± 5%. …”

Land Management Practices Associated with House Loss in Wildfires by Philip Gibbons (120631)

“…Significant fuel variables in a logistic regression model we selected to predict house loss were (in order of decreasing effect): (1) the cover of trees and shrubs within 40 m of houses, (2) whether trees and shrubs within 40 m of houses was predominantly remnant or planted, (3) the upwind distance from houses to groups of trees or shrubs, (4) the upwind distance from houses to public forested land (irrespective of whether it was managed for nature conservation or logging), (5) the upwind distance from houses to prescribed burning within 5 years, and (6) the number of buildings or structures within 40 m of houses. …”

Circadian Preference Modulates the Neural Substrate of Conflict Processing across the Day by Christina Schmidt (36805)

“…Using functional magnetic resonance imaging (fMRI), we assessed the influence of chronotype and time-of-day on conflict processing-related cerebral activity throughout a normal waking day. Sixteen morning and 15 evening types were recorded at two individually adapted time points (1.5 versus 10.5 hours spent awake) while performing the Stroop paradigm. …”

Short-term time-restricted feeding during the resting phase is sufficient to induce leptin resistance that contributes to development of obesity and metabolic disorders in mice by Katsutaka Oishi (278169)

DataSheet1_Compounds Isolated from Wikstroemia taiwanensis Regulate Bone Remodeling by Modulating Osteoblast and Osteoclast Activities.docx by Zuha Imtiyaz (11119893)

“…Specifically, astragalin (1) and kaempferol 3-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (2), besides increasing mineral deposition, increased alkaline phosphatase activity (137.2% for 1 and 115.8% for 2) and ESR-α expression (112.8% for 1 and 122.5% for 2) in primary human osteoblasts. In contrast, compounds 1, 2, 3, and 5 inhibited tartrate-resistant acid phosphatase (TRAP) activity in receptor activator of nuclear factor-κB ligand-induced osteoclasts by 40.8, 17.1, 25.9, and 14.5% and also decreased the number of TRAP-positive cells by 51.6, 26.8, 20.5, and 18.6%, respectively. …”

DataSheet1_Compounds Isolated from Wikstroemia taiwanensisRegulate Bone Remodeling by Modulating Osteoblast and Osteoclast Activities.docx by Zuha Imtiyaz (11119893)

“…Specifically, astragalin (1) and kaempferol 3-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (2), besides increasing mineral deposition, increased alkaline phosphatase activity (137.2% for 1 and 115.8% for 2) and ESR-α expression (112.8% for 1 and 122.5% for 2) in primary human osteoblasts. In contrast, compounds 1, 2, 3, and 5 inhibited tartrate-resistant acid phosphatase (TRAP) activity in receptor activator of nuclear factor-κB ligand-induced osteoclasts by 40.8, 17.1, 25.9, and 14.5% and also decreased the number of TRAP-positive cells by 51.6, 26.8, 20.5, and 18.6%, respectively. …”

Supplementary Material for: Gastrointestinal Immune Response to the Shrimp Allergen Tropomyosin: Histological and Immunological Analysis in an Animal Model of Shrimp Tropomyosin Hy... by Lam Y.F. (4153870)

“…<b><i>Background:</i></b> Shellfish hypersensitivity is among the most common food allergies. A murine model of IgE-mediated shrimp allergy has been established in our laboratory. …”

Conformational Changes of Blood ACE in Chronic Uremia by Maxim N. Petrov (118931)

Supplementary Material for: Gut microbiome composition and one-year survival outcomes among patients with reduced ejection fraction heart failure by figshare admin karger (2628495)

Fasting inhibits glycolysis and migration/invasion in gallbladder cancer via PCBP2/ANGPTL4 signaling by Ying Tao (469347)

Different influences of oxotremorine-induced rhythmicity in thoracic segments and on lumbar fictive locomotion. by Mélissa Sourioux (5492492)

“…<p>(A) In a Vaseline partitioned spinal cord (at the T13 level), bath-application of NMDA/5-HT to the lumbar compartment elicited locomotor-like activity recorded from lumbar ventral roots (A1). …”