Image_4_Synergistic Antibacterial Activity of Designed Trp-Containing Antibacterial Peptides in Combination With Antibiotics Against Multidrug-Resistant Staphylococcus epidermidis.... by Dejing Shang (8037545)

“…In addition, the antibiotics in combination with the peptide significantly inhibited biofilm formation by MRSE 1208. A mechanistic study demonstrated that the Trp-containing peptides, especially I1WL5W and I4WL5W, which contain two tryptophan residues, disrupted bacterial inner and outer membranes, which promoted antibiotic delivery into the cytoplasm and access to cytoplasmic targets; however, L11W and L12W may have increased intracellular antibiotic concentrations by decreasing blaZ, tet(m) and msrA expression. …”

Image_3_Synergistic Antibacterial Activity of Designed Trp-Containing Antibacterial Peptides in Combination With Antibiotics Against Multidrug-Resistant Staphylococcus epidermidis.... by Dejing Shang (8037545)

“…In addition, the antibiotics in combination with the peptide significantly inhibited biofilm formation by MRSE 1208. A mechanistic study demonstrated that the Trp-containing peptides, especially I1WL5W and I4WL5W, which contain two tryptophan residues, disrupted bacterial inner and outer membranes, which promoted antibiotic delivery into the cytoplasm and access to cytoplasmic targets; however, L11W and L12W may have increased intracellular antibiotic concentrations by decreasing blaZ, tet(m) and msrA expression. …”

Image_1_Synergistic Antibacterial Activity of Designed Trp-Containing Antibacterial Peptides in Combination With Antibiotics Against Multidrug-Resistant Staphylococcus epidermidis.... by Dejing Shang (8037545)

“…In addition, the antibiotics in combination with the peptide significantly inhibited biofilm formation by MRSE 1208. A mechanistic study demonstrated that the Trp-containing peptides, especially I1WL5W and I4WL5W, which contain two tryptophan residues, disrupted bacterial inner and outer membranes, which promoted antibiotic delivery into the cytoplasm and access to cytoplasmic targets; however, L11W and L12W may have increased intracellular antibiotic concentrations by decreasing blaZ, tet(m) and msrA expression. …”

Enhancing thermal and mechanical response of aluminum using nanolength scale TiC ceramic reinforcement by Reddy M.P.

“…the present work, nano-sized titanium carbide (0.5, 1.0 and 1.5 vol%) reinforced aluminum (Al) metal matrix composites were synthesized by powder metallurgy incorporating microwave sintering and hot extrusion. …”
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Inhibition of actin perturbs the kinetics of dynamin recruitment, but has minimal impact on GAK recruitment. by Marcus J. Taylor (173337)

“…(D-F) Latrunculin-B exposure decreased the peak amplitude of dynamin (D) and endo2 (E) recruitment, but had a negligible effect on the amplitude of GAK recruitment (F). …”

Stimulus-dependent concentration robustness in two-component systems. by Ronny Straube (561331)

“…<p>Steady state response curves according to <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003614#pcbi.1003614.e199" target="_blank">Eq. (31)</a> for (A and B) and (C and D). …”

Relates to Fig 2. by He Liu (67509)

“…Error bars: mean ± SEM. The raw data can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000709#pbio.3000709.s016" target="_blank">S9 Data</a>. …”

Assessment of histopathological changes induced by drug treatment in <i>Brca1</i>-wild type and -deficient tumor lines. by Ludmila Szabova (585091)

“…Tumor line 39877 was sensitive to drug treatment, which resulted in decreased proliferation (Ki67) (A e–h) and increased DNA damage (γ-H2AX) (A i–l). …”

The assessment of grip strength in preschool-aged children with and without unilateral cerebral palsy by Griet Dequeker (18059414)

Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment scores-0 by Olivier Bastien (7815)

“…In this case, the score distribution is exponential, suggesting that valine (V) is a non-aging component. Based on BLOSUM62, residues of this type are V, F, P, W, Y, E, G, H, I, L, K, R, N, D and C The score distribution shows a peak, indicating a probable accelerated process of aging (functional damage) when the residue is substituted by random mutation in some other amino acids. …”

Emergency Department presentations to NHS Lothian per week with suspected acute coronary syndrome from January to May 2019 and 2020. by Amy V. Ferry (10515233)

Data_Sheet_1_Effects of Including Sprints in One Weekly Low-Intensity Training Session During the Transition Period of Elite Cyclists.docx by Nicki Winfield Almquist (9366176)

“…Performance and physiological capacities were evaluated during a prolonged (~2.5 h) test-session, including a strength test, a submaximal blood lactate profile test, an incremental test to exhaustion to determine VO_2max, 1 h continuous cycling including four maximal 30-s sprints, and a 20-min all-out test. …”

Data_Sheet_1_Phenotypical Characteristics of the Black Yeast Exophiala dermatitidis Are Affected by Pseudomonas aeruginosa in an Artificial Sputum Medium Mimicking Cystic Fibrosis–... by Lisa Kirchhoff (5143736)

“…Experiments testing the virulence of E. dermatitidis in the greater wax moth Galleria mellonella showed a synergetic effect on larval killing when E. dermatitidis was injected together with P. aeruginosa culture filtrate. …”

The mRNA and protein expression of hepcidin in the liver. by Yasumasa Ikeda (312406)

“…<p>(A) The mRNA expression of hepcidin in the liver of OVX mice was restored by E₂ or G1 supplementation. …”

Data Sheet 1_Response surface-based media optimization for astaxanthin production in Corynebacterium glutamicum.docx by Florian Meyer (6913865)

“…</p>Methods<p>Here, a design of experiment (DoE) approach was applied to optimize the standard minimal medium for astaxanthin production. …”

Table 1_Response surface-based media optimization for astaxanthin production in Corynebacterium glutamicum.xlsx by Florian Meyer (6913865)

“…</p>Methods<p>Here, a design of experiment (DoE) approach was applied to optimize the standard minimal medium for astaxanthin production. …”

MSCs in the lung vasculature. by Shibani Pati (208746)

“…Sectioned lung tissue was stained for PDGFRβ (green) to identify pericytes or smooth muscle (SM) cells and vWF (red) to identify blood vessels. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0025171#pone-0025171-g006" target="_blank">Figures 6E and 6F</a> shows that HS and LR groups show diminished or compromised PDGFRβ staining (small white arrows), indicating decreased pericyte/SM cell coverage on microvasculature. …”

Effects of alginate on cellular iron transport. by Richard D. Horniblow (796786)

“…<p>(A) Intracellular iron concentration decreases when RKO cells were incubated with iron-59 and alginate (0.3% w/v) compared to iron only control (B) Treatment of RKO cells with iron increases ferritin expression whilst co-incubation with alginate (0.3% w/v) significantly suppressed the iron mediated ferritin induction. …”

Deregulation of p53 is associated with abnormal axonal development in neurons with genetically- or pharmacologically-induced cholesterol transport perturbation. by Qingyu Qin (251168)

“…<p><b>A&B.</b> Immunofluorescence of p53 phosphorylated at Ser15 (p-p53, green) and E6-AP (red) in hippocampal neurons cultured from E18 <i>npc1+/+</i> (<b>A</b>) or <i>npc1−/−</i> embryos (<b>B</b>) and kept for 4 days <i>in vitro</i> (DIV4). …”

Elevated CO2 Concentrations and Water Stress Affect the Ability of Italian Ryegrass to Remediate Herbicides and Enhance its Allelopathic Effect by L.P. SILVEIRA (7367411)