Hepatosteatosis in <i>ob/ob</i> mice maintained on a NASH diet does not appear affected in SR9009-treated group. by Kristine Griffett (1980421)

“…<p>Digital pathology analysis suggests that SR9009 treatment in NASH mice may not suppress total hepatic lipid area (A) or total percentage of lipids within the entire section (B). …”

DataSheet1_Solar wind magnetosonic mach number as a control variable for energy dissipation during magnetic storms.pdf by Fatemeh Bagheri (6619298)

Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model-1 by Miho Sekiguchi (89601)

“…The amount of PGEin the groups treated with loxoprofen-Na and indomethacin was decreased compared with the control group (*< 0.05) (n = 5 for naïve group; n = 6 for treatment groups).…”

Postoperative Neurocognitive Dysfunction in Patients Undergoing Cardiac Surgery after Remote Ischemic Preconditioning: A Double-Blind Randomized Controlled Pilot Study by Patrick Meybohm (20539)

“…Primary endpoint was postoperative neurocognitive dysfunction 5–7 days after surgery assessed by a comprehensive test battery. …”

Data_Sheet_1_Randomized Controlled Trials of Zhigancao Decoction Combined With Metoprolol in the Treatment of Arrhythmia: A Systematic Review and Meta-Analysis.PDF by Yan Yang (33204)

“…Moreover, mean HR reductions were reported in patients receiving ZGCD + BB the ZGCD + BB group (MD = −8.48, 95% CI: −10.98 to −5.97, P < 0.01) and a decrease in TCM symptoms were reported also (MD = −2.92, 95% CI: −3.08 to −2.76, P < 0.01). …”

The effect of a miR-762 mimic on gene expression in human corneal epithelial cells and on <i>P. aeruginosa</i> invasion. by James Mun (383662)

“…<p>a Transfection of human corneal epithelial cells with a mimic of miR-762 increased the expression of miR-762 relative to a control (scrambled) mimic, <b>b</b> decreased Rab5a mRNA expression (although that difference was not significant), <b>c</b> significantly decreased mRNA expression of RNase7 and ST-2, but not that of hBD-2 or hBD-3, and <b>d</b> increased <i>P. aeruginosa</i> invasion (* p  =  0.044, t-Test). …”

Orai3 Constitutes a Native Store-Operated Calcium Entry That Regulates Non Small Cell Lung Adenocarcinoma Cell Proliferation by Anne-Sophie Ay (458393)

“…These effects were concomitant with a down-regulation of cyclin D1, cyclin E, CDK4 and CDK2 expression. …”

Natalizumab Therapy Modulates miR-155, miR-26a and Proinflammatory Cytokine Expression in MS Patients - Fig 4 by Giuseppe Mameli (131824)

“…IL-17a, IFN γ, TNFα and IL-6 RNA expression in thirteen MS patients with miR-155 and miR-26a levels decreasing from the condition before therapy to the period following 6 months of natalizumab treatment (b; c; d; e).…”

DataSheet1_The wet scavenging of air pollutants through artificial precipitation enhancement: A case study in the Yangtze River Delta.docx by Yixuan Wu (736336)

“…After the precipitation, the number concentration of aerosols with a diameter lower than 300 nm reduces significantly, the mass concentration of particulate matter with an aerodynamic diameter less than 2.5 μm decreases by about 39%, and the mass concentrations of nitrogen dioxide, sulfur dioxide, and carbon monoxide also decrease in different degrees. …”

siRNA Silencing of Proteasome Maturation Protein (<em>POMP</em>) Activates the Unfolded Protein Response and Constitutes a Model for KLICK Genodermatosis by Johanna Dahlqvist (190279)

“…<div><p>Keratosis linearis with ichthyosis congenita and keratoderma (KLICK) is an autosomal recessive skin disorder associated with a single-nucleotide deletion in the 5′untranslated region of the proteasome maturation protein (<em>POMP</em>) gene. …”

Table 2_Effect of dietary glycemic index on insulin resistance in adults without diabetes mellitus: a systematic review and meta-analysis.docx by Yu-Ting Yu (20717441)

“…This meta-analysis included six randomized controlled trials involving 192 participants with a mean age of 52.5 years. A homeostasis model assessment of insulin resistance (HOMA-IR) score was calculated for each trial, and differences in HOMA-IR before and after each dietary intervention were calculated independently. …”

In situ observations of the influence of a large onshore wind farm on near-surface temperature, turbulence intensity and wind speed profiles - Figure 1. by Craig M Smith (557001)

“…</strong> Overview of the wind farm, including close-up views of the NE and SW locations, and schematic of the unwaked (#1, black), SW farm-waked (#2, red), SW direct-waked (#3, blue), NE farm-waked (#4, green) and NE direct-waked (#5, magenta) wind direction bins. The frequency with which flow greater than 4 ms⁻¹ was observed in the five directional sectors during 04/04/2012–05/20/2012 is 6.9, 16.6, 7.9, 14.2 and 1.8%, respectively.…”

Safety and effectiveness of ramucirumab and docetaxel: a single-arm, prospective, multicenter, non-interventional, observational, post-marketing safety study of NSCLC in Japan by Yucherng Chen (11996851)

“…The most common AEs (any grade) were malaise (14.3%), decreased appetite (13.0%), and neutrophil count decrease (11.6%). …”

Table 1_Effect of dietary glycemic index on insulin resistance in adults without diabetes mellitus: a systematic review and meta-analysis.docx by Yu-Ting Yu (20717441)

“…This meta-analysis included six randomized controlled trials involving 192 participants with a mean age of 52.5 years. A homeostasis model assessment of insulin resistance (HOMA-IR) score was calculated for each trial, and differences in HOMA-IR before and after each dietary intervention were calculated independently. …”

Site-Directed Mutations and the Polymorphic Variant Ala160Thr in the Human Thromboxane Receptor Uncover a Structural Role for Transmembrane Helix 4 by Raja Chakraborty (187863)

“…Thermal activity assays showed decrease in receptor stability in the order, wild type>A160S>A160V>A160T>G164A, with G164A being the least stable. …”

Zinc Prevents Abdominal Aortic Aneurysm Formation by Induction of A20-Mediated Suppression of NF-κB Pathway - Fig 6 by Ya-Wei Yan (2502790)

“…<p><b>The expression of the p-IKKβ, p-IκBα, IKKβ and IκBα in the abdominal aortas in vivo (A). Zinc decreased the phospho-IKKβ (B), phospho-IκBα (C) and degradation of IκBα (E).…”

Zinc Prevents Abdominal Aortic Aneurysm Formation by Induction of A20-Mediated Suppression of NF-κB Pathway - Fig 7 by Ya-Wei Yan (2502790)

“…<p><b>The expression of the p-IKKβ, p-IκBα, IKKβ and IκBα in the VSMCs in vivo (A). Zinc decreased the phospho-IKKβ (B), phospho-IκBα (C) and degradation of IκBα (E).…”

Data_Sheet_1_Toward a possible trauma subtype of functional neurological disorder: Impact on symptom severity and physical health.docx by Sara Paredes-Echeverri (14119056)

“…Participants completed self-report measures of symptom severity [Somatoform Dissociation Questionniare-20 (SDQ-20), Screening for Somatoform Disorders: Conversion Disorder subscale (SOMS:CD), Patient Health Questionniare-15 (PHQ-15)], physical health [Short Form Health Survey-36 (SF36-physical health)], childhood maltreatment [Childhood Trauma Questionnaire (CTQ)], and PTSD [PTSD Checklist-5 (PCL-5)]; a psychometric battery of other common predisposing vulnerabilities was also completed. …”

Image1_Identification and Validation of a Prognostic Risk-Scoring Model Based on Ferroptosis-Associated Cluster in Acute Myeloid Leukemia.TIFF by Jinghua Wang (101820)

“…Area under the curve values of 1, 3, and 5 years were 0.81, 0.827, and 0.786 in the training set, respectively, indicating a good predictive efficacy. …”

Image2_Identification and Validation of a Prognostic Risk-Scoring Model Based on Ferroptosis-Associated Cluster in Acute Myeloid Leukemia.TIFF by Jinghua Wang (101820)

“…Area under the curve values of 1, 3, and 5 years were 0.81, 0.827, and 0.786 in the training set, respectively, indicating a good predictive efficacy. …”