Image_3_The association between serum complement 4 and relapse of primary membranous nephropathy: a multicenter retrospective cohort study.JPEG by Wenyuan Gan (16900548)

“…</p>Result<p>515 patients with biopsy-proven PMN achieving initial remission were enrolled. 32.62% of patients subsequently relapsed during a median of 6.08 months. Lower serum albumin (Alb) (per 1 g/L decrease, hazard ratio [HR] =1.48, 95% confidence interval [CI] 1.29–1.78, p < 0.001), lower estimated glomerular filtration rate (eGFR) (per 10 mL/min/1.73m² decrease, HR =1.14, 95% CI 0.97–1.49, p < 0.001), higher serum complement 4 (C4) (per 0.1 g/L increase, HR =1.89, 95% CI 1.32–3.22, p = 0.012), partial remission (PR) (HR =2.28, 95%CI 1.74–4.04, p < 0.001), and treatment with calcineurin inhibitors (CINs) (HR =1.33, 95%CI 1.04–1.64, p < 0.001) at the time of remission were risk factors for relapse. …”

Image_1_The association between serum complement 4 and relapse of primary membranous nephropathy: a multicenter retrospective cohort study.JPEG by Wenyuan Gan (16900548)

“…</p>Result<p>515 patients with biopsy-proven PMN achieving initial remission were enrolled. 32.62% of patients subsequently relapsed during a median of 6.08 months. Lower serum albumin (Alb) (per 1 g/L decrease, hazard ratio [HR] =1.48, 95% confidence interval [CI] 1.29–1.78, p < 0.001), lower estimated glomerular filtration rate (eGFR) (per 10 mL/min/1.73m² decrease, HR =1.14, 95% CI 0.97–1.49, p < 0.001), higher serum complement 4 (C4) (per 0.1 g/L increase, HR =1.89, 95% CI 1.32–3.22, p = 0.012), partial remission (PR) (HR =2.28, 95%CI 1.74–4.04, p < 0.001), and treatment with calcineurin inhibitors (CINs) (HR =1.33, 95%CI 1.04–1.64, p < 0.001) at the time of remission were risk factors for relapse. …”

Table_1_The association between serum complement 4 and relapse of primary membranous nephropathy: a multicenter retrospective cohort study.DOCX by Wenyuan Gan (16900548)

“…</p>Result<p>515 patients with biopsy-proven PMN achieving initial remission were enrolled. 32.62% of patients subsequently relapsed during a median of 6.08 months. Lower serum albumin (Alb) (per 1 g/L decrease, hazard ratio [HR] =1.48, 95% confidence interval [CI] 1.29–1.78, p < 0.001), lower estimated glomerular filtration rate (eGFR) (per 10 mL/min/1.73m² decrease, HR =1.14, 95% CI 0.97–1.49, p < 0.001), higher serum complement 4 (C4) (per 0.1 g/L increase, HR =1.89, 95% CI 1.32–3.22, p = 0.012), partial remission (PR) (HR =2.28, 95%CI 1.74–4.04, p < 0.001), and treatment with calcineurin inhibitors (CINs) (HR =1.33, 95%CI 1.04–1.64, p < 0.001) at the time of remission were risk factors for relapse. …”

Image_4_The association between serum complement 4 and relapse of primary membranous nephropathy: a multicenter retrospective cohort study.JPEG by Wenyuan Gan (16900548)

“…</p>Result<p>515 patients with biopsy-proven PMN achieving initial remission were enrolled. 32.62% of patients subsequently relapsed during a median of 6.08 months. Lower serum albumin (Alb) (per 1 g/L decrease, hazard ratio [HR] =1.48, 95% confidence interval [CI] 1.29–1.78, p < 0.001), lower estimated glomerular filtration rate (eGFR) (per 10 mL/min/1.73m² decrease, HR =1.14, 95% CI 0.97–1.49, p < 0.001), higher serum complement 4 (C4) (per 0.1 g/L increase, HR =1.89, 95% CI 1.32–3.22, p = 0.012), partial remission (PR) (HR =2.28, 95%CI 1.74–4.04, p < 0.001), and treatment with calcineurin inhibitors (CINs) (HR =1.33, 95%CI 1.04–1.64, p < 0.001) at the time of remission were risk factors for relapse. …”

Table1_Transcatheter aortic valve implantation (from inception to standard treatment): a single-center observational study.docx by Martin Petter Høydahl (17787152)

“…The early mortality rates were 5.6%, 5.8%, and 6.5%, respectively. No significant differences were observed in late mortality by sex or age group (<70, 70–79, and 80–89 years) with a median survival of 5.3–5.6 years. …”

Dental developmental complications in pediatric hematopoietic stem cell transplantation patients: A study using CMC clinical data warehouse by Jaehyun Kim (14009967)

“…When grouped according to the age at initial chemotherapy (≤ 2.5; 2.6–5.0; 5.1–7.5; >7.5 years), the prevalence of agenesis showed statistically significant differences among the different age groups (P<.001). …”

Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Video 1_Case report: A severe myositis mimicking bulbar palsy after administration of immune checkpoint inhibitors.mp4 by Philippe Rochigneux (10671993)

“…In a multidisciplinary setting, she was treated with IV corticosteroids (methylprednisolone 1 mg/kg started at day 10, with a progressive decrease until 1 mg of prednisone in March 2024), IV immunoglobulins started at day 18 (1.5 g/kg in 2 days, administered monthly, with a progressive decrease and a cessation in June 2022), enteral nutrition, speech therapy and physical therapy, with noticeable improvement. …”

Data_Sheet_1_Cancer Related Subarachnoid Hemorrhage: A Multicenter Retrospective Study Using Propensity Score Matching Analysis.docx by Shijian Chen (1609249)

“…Logistic regression revealed that a decrease in platelet and prolonged prothrombin time were the independent risk factors of cancer related SAH. …”

Data Sheet 1_The impact of a home visiting program on the care environment of Brazilian adolescent mothers - an descriptive exploratory study.pdf by Letícia Aparecida da Silva (21178136)

“…From 12 to 24 months, both groups showed a tendency for the median to decrease, with a more marked decrease in the CG, which reached values lower than those previously observed. …”

FluidFM-mediated injections of liquids and bacteria into enteroid-derived IECs. by Chantal Ernst (9953921)

“…Focused ion beam image of a FluidFM tip: Scale bar: 5 μm. (<b>B</b>) Dye injection into single IECs. …”

Western blotting analysis showing the effects of Pioglitazone and LPSF/GQ-02 on the expression of PPARα and PPARγ in the liver of LDLR-/- mice. by Amanda Karolina Soares e Silva (723276)

“…<p>Treatment for 15 days did not alter the expression of PPARα (A, B). However, in the 30-day experiment, the HFD and LPSF/GQ-02 groups exhibited a decrease in the expression of PPARα when compared to the control groups (D, E). …”

Data_Sheet_1_Electroacupuncture for post-stroke urinary incontinence: a systematic review and meta-analysis with trial sequential analysis.docx by Zefei Jiang (3523967)

“…In comparison to basic treatments combined with active interventions, the amalgamation of EA and them led to an increase in the responder rate (RR 1.24, 95% CI 1.14 to 1.35, p < 0.00001), a reduction in 24-h urinary incontinence occurrences (MD −2.90, 95% CI −5.26 to −0.55, p = 0.02), a decrease in International Consultation on Incontinence Questionnaire-Short Form scores, and an improvement in both MCC (MD 42.11, 95% CI 23.26 to 60.96, p < 0.0001) and RUV (MD 42.11, 95% CI 23.26 to 60.96, p < 0.0001). …”

Non-indigenous seaweeds in the Northeast Atlantic Ocean, the Mediterranean Sea and Macaronesia: a critical synthesis of diversity, spatial and temporal patterns by Luna M. van der Loos (17462429)

“…In so far as analyses of first detections can serve as a proxy for the introduction rate of non-indigenous seaweeds, these do not reveal a decrease in the introduction rate, indicating that the current measures and policies are insufficient to battle the introduction and spread of non-indigenous species in the study area.…”

Spatio-temporal changes in expression of pluripotency markers and self-organization of stem cell-derived aggregates in 3D culture. by Rachel E. DeJonge (3109986)

“…<p>(A-D) Expression of the pluripotency marker Nanog decreases as vesicles mature between differentiation days 5–8. …”

Genome-wide occupancy of SAGA subunits in ovary tissue shows that SAGA broadly binds to active promoters. by Jelly H. M. Soffers (11740713)

Characteristics of the study subjects (N = 39). by Layane S. P. Costa (22530327)

“…</p><p>Trial registration</p><p>ClinicalTrials.gov [<a href="https://clinicaltrials.gov/ct2/show/NCT06044896" target="_blank">NCT06044896</a>]</p></div>…”

Flowchart of study. by Layane S. P. Costa (22530327)

“…</p><p>Trial registration</p><p>ClinicalTrials.gov [<a href="https://clinicaltrials.gov/ct2/show/NCT06044896" target="_blank">NCT06044896</a>]</p></div>…”