Structural and functional dissection reveals distinct roles of Ca²⁺-binding sites in the giant adhesin SiiE of <i>Salmonella enterica</i> by Britta Peters (4054456)

“…Amounts of secreted SiiE diminish with a decreasing number of intact Ca²⁺-binding sites. …”

Ca²⁺ binding mutants had differential effects on evoked and spontaneous release. by Mallory C. Shields (4474210)

“…<p><b>A</b>. Representative EJP traces from <i>P[syt^WT]</i>, <i>P[syt^D-N]</i>, and <i>P[syt^D-E]</i>. …”

Exposure to hyperoxia induces features of BPD-PH in newborn rats. by Eric Dumas de la Roque (3779935)

“…<p>(A) Right ventricle systolic pressure (RSVP) was significantly increased by hyperoxia (<i>n</i> = 18) compared with normoxia (<i>n</i> = 9). …”

Analysis of dpMPK-1 spatial expression in N2 <i>C</i>. <i>elegans</i> hermaphrodite germline after chronic exposure to IR at different life-stages. by Elizabeth Dufourcq Sekatcheff (17457627)

Phenotype Accessibility and Noise in Random Threshold Gene Regulatory Networks by Ricardo Pinho (171472)

“…We used a generic model of organismal development --gene regulatory networks-- to investigate how different levels of noise on gene expression states (i.e. phenotypes) may affect access to new, unique phenotypes, thereby affecting phenotypic diversity. …”

Hazard ratios of cardiovascular outcomes, with 95% confidence intervals, for deciles of the apoB/apoA-1 ratio. by Göran Walldius (286838)

The genotoxicity of K₂CrO₄ in human and DT40 cells is drastically decreased when K₂CrO₄ incubation time is reduced. by Xu Tian (179192)

Flexible Sheet-Type Sensor for Noninvasive Measurement of Cellular Oxygen Metabolism on a Culture Dish - Fig 5 by Mari Kojima (832141)

“…Scale bar: 50 μm. (b)-(e) Bright-field images of MCF7 and flexible sensor sheet. …”

Small Angle Neutron Scattering Studies of R67 Dihydrofolate Reductase, a Tetrameric Protein with Intrinsically Disordered N‑Termini by Purva P. Bhojane (1839205)

“…From a combined analysis using molecular dynamics and the program SASSIE (http://www.smallangles.net/sassie/SASSIE_HOME.html), the apoenzyme displays a radius of gyration (<i>R</i>_g) of 21.46 ± 0.50 Å. …”

Small Angle Neutron Scattering Studies of R67 Dihydrofolate Reductase, a Tetrameric Protein with Intrinsically Disordered N‑Termini by Purva P. Bhojane (1839205)

“…From a combined analysis using molecular dynamics and the program SASSIE (http://www.smallangles.net/sassie/SASSIE_HOME.html), the apoenzyme displays a radius of gyration (<i>R</i>_g) of 21.46 ± 0.50 Å. …”

Mesenchymal ablation at e13.5 leads to reduced β- and acinar-cell mass due to impaired proliferation of precursor cells. by Limor Landsman (206879)

“…(A) A scheme illustrating embryonic development from e9.5 to e18.5. …”

mRNA expression of osteogenic, chondrogenic and proinflammatory genes. by Masayuki Kamimura (748092)

Impaired bone formation in <i>Col1a1-Krm2</i> transgenic mice. by Jochen Schulze (365258)

“…<p>(A) Toluidine blue staining of non-decalcified vertebral body sections from 6 weeks old female wildtype and <i>Col1a1-Krm2</i> transgenic littermates revealing that the normal appearance of cuboidal osteoblasts (arrows) covering trabecular bone surfaces is only observed in wildtype controls (scale bars, 50 µm). …”

Brainsci-3357138 by SEONGHAN KIM (19824351)

“…Furthermore, the expression of Cdc42EP2 protein was suppressed by E46K α-syn, leading to decreased βIII-tubulin levels, which was opposite to the effect of WT and A53T α-syn. …”

Brainsci-3272850 by SEONGHAN KIM (19824351)

“…Furthermore, the expression of Cdc42EP2 protein was suppressed by E46K α-syn, leading to decreased βIII-tubulin levels, which was opposite to the effect of WT and A53T α-syn. …”

Image1_Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation.jpeg by Tung D. Nguyen (17388664)

“…We find that a single amino acid substitution at the eNOS S1176 phosphorylation site yields divergent effects on atherosclerotic plaque formation, as an eNOS phospho-mimic aspartate (D) substitution at S1176 leads to favorable lipid profiles and decreased indices of atherosclerosis, even when on a proatherogenic Akt1 global deletion background. …”

Image3_Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation.jpeg by Tung D. Nguyen (17388664)

“…We find that a single amino acid substitution at the eNOS S1176 phosphorylation site yields divergent effects on atherosclerotic plaque formation, as an eNOS phospho-mimic aspartate (D) substitution at S1176 leads to favorable lipid profiles and decreased indices of atherosclerosis, even when on a proatherogenic Akt1 global deletion background. …”

Image4_Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation.jpeg by Tung D. Nguyen (17388664)

“…We find that a single amino acid substitution at the eNOS S1176 phosphorylation site yields divergent effects on atherosclerotic plaque formation, as an eNOS phospho-mimic aspartate (D) substitution at S1176 leads to favorable lipid profiles and decreased indices of atherosclerosis, even when on a proatherogenic Akt1 global deletion background. …”

Image5_Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation.jpeg by Tung D. Nguyen (17388664)

“…We find that a single amino acid substitution at the eNOS S1176 phosphorylation site yields divergent effects on atherosclerotic plaque formation, as an eNOS phospho-mimic aspartate (D) substitution at S1176 leads to favorable lipid profiles and decreased indices of atherosclerosis, even when on a proatherogenic Akt1 global deletion background. …”

Image6_Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation.jpeg by Tung D. Nguyen (17388664)

“…We find that a single amino acid substitution at the eNOS S1176 phosphorylation site yields divergent effects on atherosclerotic plaque formation, as an eNOS phospho-mimic aspartate (D) substitution at S1176 leads to favorable lipid profiles and decreased indices of atherosclerosis, even when on a proatherogenic Akt1 global deletion background. …”