Increasing TPP side chain length decreases melanoma cell viability and clonogenic survival. by Kyle C. Kloepping (9928265)

“…A375 melanoma cells were treated with 0.25 μM, 0.5 μM, or 1.0 μM 5-, 8-, 10-, 12-,14-, or 16-TPP for (C) 24 h and (D) 48 h and analyzed for clonogenic survival (* represents when 12-, 14-, and 16-TPP were significant relative to 5-TPP and 8-TPP; Ψ represents when 10-TPP was significant relative to 5-TPP and 8-TPP; p < 0.05; n = 3 from 2 separate experiments; N = 6). …”

TEM4 depletion decreases TEM4 mRNA and protein levels but no effect on spindle staining by the TEM4 antibody. by Diogjena Katerina Prifti (12988141)

Reduced callose synthesis in <i>pat</i> is associated with the decreased <i>CalS5</i> expression. by Shuang-Xi Xiong (8844044)

Conditional <i>Aff4</i> knockout decreases fat mass in mice. by Yaqian Chen (1711576)

Activating cAMP synthesis decreases liberation of propionyl-CoA from cholesterol. by Kaley M. Wilburn (12060476)

Inactivation of one allele of FT5. by Sophia Bigot (16469992)

Muscle-specific knockdown of <i>nSMase</i> decreases a subset of ceramide species that are decreased in <i>Gba1b</i> mutants. by Kathryn A. Jewett (3756811)

The A1 mutation decreases antisense transcriptional activity of the LTR in OVK cells. by Thomas Joris (13224720)

WT data of set A398E/V and set M1425V/I pooled for better comparison. by Yousra El Ghaleb (22075892)

Subjects:

Over time, melanization decreases with aging, higher temperature, and infection. by Lindsay E. Martin (17377067)

CR increases ROS and decreases the mtDNA copy number in MLH1 deficient cells. by Berna Somuncu (12770334)

IFN-β signalling pathway stimulation by Poly(I:C) decreased 5’terminally deleted CVB3 RNA forms viral loads, cardiac lesions and mortality in DBA/2J mice. by Domitille Callon (17723936)

Osr1 heterozygous mice experienced decreased bile acid synthesis in the liver. by Ernest C. Lynch (12769954)

“…(C). Combined results of Osr1 male and female mice show a decreased trend of hepatic bile acid compared to WT mice. …”

Chronic high glucose induces apoptosis and proteasome activities decrease in INS-1E cells. by Christophe Broca (538652)

Cardamonin decreased the content of free fatty acids and the activity of CPT-1. by Peiguang Niu (17044532)

Cardamonin decreased the protein level of Raptor and suppressed lipogenesis and CPT-1. by Peiguang Niu (17044532)

Coronavirus replication is decreased in AMPK-knockout (KO) cells. by Minsu Jang (2817730)

Spatial information of excitatory neurons in APP/PS1 mice are decreased in dCA1 and vCA1. by Udaysankar Chockanathan (18510288)

“…<p>(A) In dCA1, spatial information was decreased in APP/PS1 mice relative to C57BL/6 controls (mean ± std: C57BL/6 = 0.134 ± 0.050, APP/PS1 = 0.132 ± 0.054, p < 0.01, two-sided Wilcoxon rank-sum test, n_C57BL/6 = 229 units from 5 recording sessions, n_APP/PS1 = 124 units from 4 recording sessions). …”

Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

SARS-CoV-2 decreases excitatory synapses, while influenza A does not induce cell death in BCO. by Pinar Mesci (14053895)