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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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AMPs are increased in lesional HS, but DCD and other sweat-gland associated proteins are decreased.
Published 2019“…<p>(A) Volcano plot showing increased or decreased genes in HS. …”
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Genes whose expression was decreased by 100 nM ouabain by more than 1.3-fold.
Published 2019“…<p>Genes whose expression was decreased by 100 nM ouabain by more than 1.3-fold.</p>…”
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Long COVID prevalence decreases with vaccine uptake in the U.S.
Published 2023“…<p>(A) Prevalence in U.S. states and the U.S. exhibits a decreasing trend with respect to vaccine uptake, both in the population vaccinated with at least one dose (top) and two doses (bottom), with the largest gap between 100% vaccinated and 100% unvaccinated scenarios observed in the reference population of adults who had COVID-19. …”
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Heat map showing time dependent changes for all genes with a ≥ 2-fold maximal increase or decrease in gene expression (mRNA) in response to single doses of IFN-γ.
Published 2022“…<p>Gene expression for each gene averaged across subjects are shown in order from pre (T0) or post (T1-8) IFN-γ administration as well as by dose (10, 25, 50 and 100mcg/m<sup>2</sup> respectively). The cells are colored according to expression level relative to row (i.e., relative within gene). …”
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The <i>rcan-1</i> rearrangement allele decreases expression of <i>rcan-1</i>.
Published 2020“…The gene with the largest and most significant expression decrease was <i>rcan-1</i>. Red: p<0.01, log<sub>2</sub>(Fold Change) > 1. …”
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GSK343 decreased tumor stemness.
Published 2021“…<p>(A) COA3 and (B) COA6 PDX cells were plated as single cell suspension in serum-free, conditioned media onto 96-well low attachment plates using serial dilutions with 5000, 1000, 100, 50, 20, 10, and 1 cell per well. …”
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Repetitive stress induces a decrease in sound-evoked activity.
Published 2025“…Marked at time = 0 is the onset of the 100-ms white noise. (f) A second group of mice followed the same procedures but without experiencing daily restraint stress (<i>N</i> = 3 mice, <i>n</i> = 123 neurons). …”
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