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Fig 4 -
Published 2024“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”
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AMPs are increased in lesional HS, but DCD and other sweat-gland associated proteins are decreased.
Published 2019“…<p>(A) Volcano plot showing increased or decreased genes in HS. …”
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(R+S) and (R)-albuterol decrease NF-κB activity
Published 2011“…After transfection, (R)-albuterol (R), (S)-albuterol (S), or racemic albuterol (R+ S) were added to cells pre-activated with (ConA, 5 μg/ml) and (PMA, 100 ng/ml) (CP) and then treated with (R)-, (S)-, or (R+S)-albuterol (Fig. 6). …”
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(R)-albuterol decreases cytokine levels in activated murine splenocytes
Published 2011“…</p><p></p> (R)-albuterol (R), (S)-albuterol (S) or racemic albuterol (R + S) at a dose (10M) were added to murine splenocytes pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP), (Fig 3 A, B). …”
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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Statistically significant correspondence between human psoriasis and mouse psoriasiform phenotypes: Proportion of psoriasiform-increased to psoriasiform-decreased transcripts.
Published 2011“…Likewise, we identified 533 transcripts with significantly decreased expression in human psoriasis (FDR-adjusted P<0.05 and log<sub>2</sub>-transformed fold-change estimate less than 1.00 in absolute value), and these transcripts were associated with 709 transcripts derived from orthologous mouse genes. …”
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