DUOX activation upon HPx1 silencing and hierarchical mode of activation of innate immunity in the mosquito midgut. by Octavio A. C. Talyuli (4285141)

Distinct effects on calcium channel activation of <i>CACNA1I</i> disease-associated amino acid substitutions A398E/V and M1425V/I. by Yousra El Ghaleb (22075892)

Subjects:

S3 Fig - by Octavio A. C. Talyuli (4285141)

28 days of testosterone depletion decreases fiber CSA only in the TA muscle and only at 1.5-month-old mice. by Arik Davidyan (10450896)

PMNs derived from either GF mice or mice treated with oral antibiotics have significantly decreased bactericidal activities against <i>P</i>. <i>aeruginosa</i> and altered transcri... by Abirami Kugadas (3131940)

Muscle-specific knockdown of <i>nSMase</i> minimally decreases glucosylceramide levels, which are globally elevated in <i>Gba1b</i> mutants. by Kathryn A. Jewett (3756811)

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa by Andrej Emanuel Cotman (5203904)

“…Starting from DNA gyrase inhibitor <b>1</b>, we identified compound <b>27</b>, featuring a 10-fold improved aqueous solubility, a 10-fold improved inhibition of topoisomerase IV from A. baumannii and P. aeruginosa, a 10-fold decreased inhibition of human topoisomerase IIα, and no cross-resistance to novobiocin. …”

Basal and radiation-induced ROS in DC lymphocytes. by Larisa Pereboeva (322533)

Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments by Animesh Gopal (18521180)

“…Incorporation of poly­(butylene adipate-<i>co</i>-terephthalate) (PBAT) along with maleic anhydride grafted polypropylene (MAPP) in specific proportions led to a significant enhancement in mechanical properties, miscibility, crystallization behavior, and 3D printability. rPP/PBAT blends with 20 wt % PBAT and 10 wt % MAPP exhibited a 62-fold enhancement in elongation at break over rPP (from 1.88 to 118.29%) and a 72-fold increase in toughness (from 2 to 143.60 kJ/m³) with almost similar tensile strength. …”

Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments by Animesh Gopal (18521180)

“…Incorporation of poly­(butylene adipate-<i>co</i>-terephthalate) (PBAT) along with maleic anhydride grafted polypropylene (MAPP) in specific proportions led to a significant enhancement in mechanical properties, miscibility, crystallization behavior, and 3D printability. rPP/PBAT blends with 20 wt % PBAT and 10 wt % MAPP exhibited a 62-fold enhancement in elongation at break over rPP (from 1.88 to 118.29%) and a 72-fold increase in toughness (from 2 to 143.60 kJ/m³) with almost similar tensile strength. …”

ADGF-A expression during infection. by Adam Bajgar (730380)

RelA–TA2 docks itself onto a series of interlinked hydrophobic grooves of TAZ1 through a number of hydrophobic residues, which serve as anchor points. by Sulakshana P. Mukherjee (453389)

“…<p>Disruption of any of the anchor points leads to the destabilization of the whole binding architecture of the complex. ∼2,800 Ų of RelA–TA2 surface area are buried upon formation of RelA–TA2:TAZ1 complex. …”

<i>S.</i> Typhimurium-infected mice have tissue inflammation and thrombosis, increased hematopoiesis, and decreased splenic iron. by Diane E. Brown (160264)

“…The infected mouse had 11.5-fold more TER119^med pro-erythroblasts and 5.5-fold more TER119^high erythroblasts than the mock-infected mouse. …”

AgLDL induce the decrease of ΔΨm and ATP in THP-1 macrophages, without mtROS or apoptosis. by Gabriela M. Sanda (10031559)

S C-terminal mutations that decrease ezrin interaction enhance transduction by pseudotyped particles in Vero E6 cells. by Jean Kaoru Millet (117227)

Rhox5 decreases UNC5C expression. by Mayumi Sugimoto (151133)

Decreased dCAP-D3 levels result in spreading of repressive histone marks and an opening of the chromatin at a dCAP-D3 regulated gene cluster containing a retrotransposon. by Andrew T. Schuster (478446)

“…(B) qRT-PCR for transcript levels of genes surrounding <i>mdg1-1403</i> (as depicted in diagram in A) indicates that compared to control dsRNA treated cells, transcription is decreased in dCAP-D3 dsRNA treated cells prior to retrotransposon mobilization (day 4) and increases to almost normal levels on the day of retrotransposon mobilization (day 5). …”

Maternal Hypoxia Decreases Capillary Supply and Increases Metabolic Inefficiency Leading to Divergence in Myocardial Oxygen Supply and Demand by David Hauton (341981)

“…Hearts of male offspring subjected to Maternal Hypoxia showed a 20% decrease in cardiac output (<i>P</i><0.05), despite recording a 2-fold increase in glucose oxidation (<i>P</i><0.01) and 2.5-fold increase (<i>P</i><0.01) in palmitate oxidation. …”

Exposure to EtBr decreases mtRNA in rat striatal co-cultures, purified neuronal cultures, and astrocytes. by Emily Booth Warren (4276333)

“…<p>(A-C) Log2-fold decrease in mtRNA expression after EtBr treatment assayed with RNASeq, in (A) NECos, (B), pure neuronal cultures, and (C) astrocytes. …”

DOM assembly monitored with temperature and pH reveals that, as either pH decreases or temperature increases, microgel equilibrium size and assembly rates decrease at a non-linear... by Chi-Shuo Chen (234719)