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Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41
Published 2011“…Indeed, Nef and Glycosylated-Gag decreased the efficiency of virion capture by 2F5 and 4E10, but not by other nAbs. …”
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Proinflammatory signaling pathways were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters.
Published 2022“…<p><b>(A)</b> Boxplots of SARS-CoV-2 transcripts normalized read counts across all animals, vaccinated hamsters are shown in blue and pink, and sham animals in green. …”
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PDGF-BB maintains Bcl2/Bax ratio and decreases caspase-3 activation induced by Tat and morphine.
Published 2011“…(B) Densitometric analysis of the blots shown in (A). Tat and morphine together resulted in a significantly decreased ratio of Bcl2/Bax, indicating cell's progress towards apoptosis. …”
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Allelic loss of <i>Cdh11</i> led to faster growing tumors due to decreased cell death.
Published 2010“…<p>(A) The number of single tumor initiating cells at PND8 was estimated by averaging the total number of TAg-positive cells in 5 mice per genotype. …”
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Dispersion-temperature of microgels decreases at lower pHs.
Published 2015“…Dispersion temperature dropped ~2˚C with a 0.2 pH decrease. Each data point represents mean (+/−SD) of six measurements made in each of six replicate samples.…”
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Intravitreal ALF-186 decreased the IRI-induced capsase-3 and NF-κB mRNA expression and affected the heat-shock response differently.
Published 2017“…<p><b>(A)</b> Fold induction of caspase-3 mRNA expression after PBS, ALF-186, or iALF injection after IRI compared to GAPDH in relation to the corresponding non-ischemic contralateral retina analyzed by RT-PCR (n = 6; mean±SD; *** = p<0.001; *** = p<0.001). …”
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Drugs which cluster on the 'anxiolytic' group decrease 5-HT turnover in the brain.
Published 2014“…A negative correlation is found between the decrease in serotonin turnover and the increase in time on white produced by a drug (r<sup>2</sup> = 0.5688, p = 0.0073).…”
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The 5’SS motif decreases mRNA stability and promotes nuclear retention.
Published 2015“…Note that the relative level of <i>c-ftz-Δi-V5-His</i> decreases over the first 60 min until 40–50% of the mRNA remains, after which point the ratio is stable. …”
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Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons.
Published 2025“…The number of branch points in PV interneuron axons from cuprizone-treated mice was significantly decreased compared to control mice (<i>t test; n = 10/9 cells per group, *p < 0.05</i>). …”
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Validation of a New Scoring Scale for Behavioral Assessment of L‑Dopa-Induced Dyskinesia in the Rat: A New Tool for Early Decision-Making in Drug Development
Published 2017“…The rating scale was sensitive enough to highlight a dose-dependent amantadine-mediated decrease (about 2.2-fold) in LID score. …”