<i>Ex vivo</i> deletion of <i>sirt1</i> decreases expression of RUNX2 downstream targets. by Kayvan Zainabadi (502381)

“…<b>C)</b> While SIRT1 knockout osteoblasts (Cre) express comparable amounts of Runx2, they show a near two-fold reduction in the expression of the Runx2 downstream target, <u>Osterix</u> (Osx). …”

a) ECM components and collagen structure change with tumor progression, which influences cancer cell proliferation and metastasis. b) SHG visual representation of collagen patterns... by Zoë Dinkel (21402766)

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

siRNA knockdown of HDAC1 in virus producer cells results in decreased infectivity of HIV-1 in target cells. by Masha Sorin (263194)

Inhibition of autophagic flux increases EtOH-induced oxidative stress, induces mitochondrial depolarization, and decreases cell viability. by Prasanna M. Chandramouleeswaran (3176268)

Time concordance metrics for all TFs, pathways as well as genes using both a minimal |logFC| of 0.5 and 1. by Anika Liu (8411805)

Constitutive KIT activation in cells with gain-of function KIT mutations causes increased ROS levels and decreased DJ-1. by Do-Kyun Kim (2176492)

HvPIN1a localisation is influenced by BFA and its expression is decreased by cytokinin. by Gwendolyn K. Kirschner (5142644)

Models of G48D, M78I, G125C, and A146V RAD52 point mutants. by Abdulaziz B. Hamid (13804692)

Resveratrol decreased tumor latency in <i>Sirt1^Y/+</i> mice. by Katherine V. Clark-Knowles (368164)

Gene expression analysis of oxidative stress-related genes in A375 melanoma cells over-expressing hMp84. by Daniele Moretti (379766)

Glu58 and Arg87 minimal distance decreases upon activation. by Maxime Louet (150102)

M344 decreases orthotopic pancreatic tumor growth when used as a treatment alone or in combination with gemcitabine. by Shelby M. Knoche (13833807)

Eltrombopag markedly decreases levels of ROS in MOLM14 cells. by Anna Kalota (7415)

“…B) Graphic presentation of ROS levels measured by flow cytometry in cells treated with E (5 μM) or DPI (25 μM), an inhibitor of NADPH oxidase known to decrease an intracellular level of ROS, or untreated (CTR) cells. …”

Compared to vorinostat, M344 decreases pancreatic cancer cell proliferation more effectively for a longer duration. by Shelby M. Knoche (13833807)

Additional behavioral patterns in the 5€, 100€, and 1000€ treatments. by Pablo Brañas-Garza (336425)

Cardiac developmental defects observed in zebrafish treated with cigarette smoke. by Nathan J. Palpant (127912)

Scatterplot of fold-change expression for T-cell-specific mRNA transcripts in the whole blood. by Luísa Camacho (5508251)

“…The horizontal gray bars indicate a 2-fold increase and decrease in expression compared to control. …”

TRIM5 restriction of HIV-1 has decreased during evolution leading to humans. by Michael Emerman (12304)

“…Original data is found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000301#pbio.1000301-Goldschmidt1" target="_blank">[30]</a> and shows that the antiviral gene TRIM5 restricted HIV-1 better at points in evolution earlier than the chimp–human common ancestor than it does after that. …”

Δ<i>ptsI</i> mutants are impaired for intramacrophage growth and virulence, with more decreased virulence in a Δ<i>glpD</i>/Δ<i>golD</i>/Δ<i>uhpT</i> background and can be trans-co... by Matthew J. Freeman (21094788)