L1 animals lacking <i>adr-2</i> have decreased expression of genes regulated by insulin signaling. by Ananya Mahapatra (17041557)

APB5, but not APA5, decreases proliferating cell numbers in inter-alveolar spaces of lungs. by Masami Kishi (6167105)

Rdh10a deficient embryos have decreased expression of RA signaling responsive genes. by Enrico D’Aniello (798447)

“…<p>(A-F) ISH for <i>cyp26a1</i>, <i>hoxb5b</i>, <i>and dhrs3a</i> expression in control sibling and Rdh10a deficient embryos. …”

a-c: Bone marrow (BM) HIF2 α is inappropriately decreased in uremic anemia. by Daniel Landau (440830)

“…<p>BM HIF2 α protein (depicted as percentage of actin-corrected concentration) increases in 7 day-bled rats (Fig 2a) Vs control. Contrary to that, BM HIF2 α protein decreases in uremic (4 weeks after 5/6 nephrectomy) rats (Fig. 2b). …”

Time adjusted survival curves for high vs. low renalase among patients with COVID-19 disease (using first quartile as cutoff). by Basmah Safdar (12213257)

CD5-2 decreases established CCM lesions in the hindbrain of <i>Ccm2</i>^<i>ECKO</i> mice and lesions in the retina of <i>Ccm2</i>^<i>ECKO</i> mice. by Jia Li (160557)

Cox hazard regression model of renalase and primary composite outcome. by Basmah Safdar (12213257)

<i>Ex vivo</i> deletion of <i>sirt1</i> decreases expression of RUNX2 downstream targets. by Kayvan Zainabadi (502381)

“…<b>C)</b> While SIRT1 knockout osteoblasts (Cre) express comparable amounts of Runx2, they show a near two-fold reduction in the expression of the Runx2 downstream target, <u>Osterix</u> (Osx). …”

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-2 by Mrigank Srivastava (94935)

“…(A), data are given as fold change in cathepsin K mRNA of bleomycin-challenged cath K tg mice compared to wild-type mice. …”

Spinal cord of CCI-mice treated with EGCG and compound 30 at 14 dpi showed decreased levels of inflammatory cytokines by Xavier Xifró (719821)

TQ decreases CXCR4 expression on MM cells and CXCL12-induced CXCR4/CD45 association. by Gamal Badr (113166)

Reduction of Tks5 expression in tumor cells is associated with decreased angiogenesis. by Barbara Blouw (715467)

IFNAR1 is decreased on CD103⁺ DCs in the PPs of mice following treatment with La-IFN-β. by Adelle P. McFarland (229619)

IRE1 depletion decreases heterochromatin, DNA and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

Characterization of CFDP1-H2A.Z interaction. by Gokul Gopinathan (7930679)

“…(E) CFDP1 depletion led to a remarkable reduction in chromatin incorporation of exogenously supplied FLAG-H2A.Z compared to control siRNA (con si)-treated cells (<2.5-fold). …”

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

Receptor for advanced glycation end-products and World Trade Center particulate induced lung function loss: A case-cohort study and murine model of acute particulate exposure - Fig... by Erin J. Caraher (4445902)

Regadenoson increases survival of SARS-CoV-2-infected K18-mice. by Joseph Rabin (7399436)

Subjects:

Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

Inhibition of autophagic flux increases EtOH-induced oxidative stress, induces mitochondrial depolarization, and decreases cell viability. by Prasanna M. Chandramouleeswaran (3176268)