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641
Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism
Published 2019“…However, the mechanisms by which GABAergic system dysfunctions induce the pathophysiology of ASD remain unclear. We previously demonstrated that a selective type I 5α-reductase inhibitor SKF105111 (SKF) induced ASD-like behaviors, such as impaired sociability-related performance and repetitive grooming behaviors, in male mice. …”
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642
Sarcopenia as an Independent Risk Factor for Decreased BMD in COPD Patients: Korean National Health and Nutrition Examination Surveys IV and V (2008-2011)
Published 2016“…<div><p>Background</p><p>A decrease in bone mineral density (BMD) is a systemic consequence of chronic obstructive pulmonary disease (COPD). …”
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643
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644
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645
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648
Quantitative assays of decreased LncRNAs in I/R-treated mouse plasma.
Published 2015“…<p>A-E) Five downregulated LncRNAs with most meaningful decrease in expression fold picked up by microarray assays were further analyzed and confirmed by quantitative RT-PCR assay. …”
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649
RT-qPCR analysis of congenital diaphragmatic hernia lungs showed an increase in distal epithelial progenitor and a decrease in type 1 alveolar cells.
Published 2019“…<p>E17.5 CDH lungs demonstrated a decrease in mRNAs identifying alveolar epithelial type I cells (<i>Hopx</i>, <i>Pdpn</i>) while distal epithelial progenitor marker <i>Id2</i> was increased. …”
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650
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651
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653
Total history dependence decreases for small time bins Δ<i>t</i>.
Published 2021“…The smaller the time bin, the higher the risk that noise in the spike emission reduces the overall predictability or history dependence in the spiking, whereas an overly large time bin holds the risk of destroying coding relevant time information in the spike train. Thus, we chose the smallest time bin Δ<i>t</i> = 5 ms that does not yet show a substantial decrease in <i>R</i><sub>tot</sub>. …”
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654
GFRα2 expression was dramatically decreased in Runx1 knockout mice.
Published 2013“…*<i>p</i><0.05; t-test. <b>C</b>) Five days after sciatic nerve axotomy, Runx1 expression decreased in ipsilateral DRG (<b><i>C<sup>/</sup></i></b>) relative to contralateral DRG (<b><i>C</i></b>). …”
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655
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656
Decreased Polycystin 2 Levels Result in Non-Renal Cardiac Dysfunction with Aging
Published 2016“…Here, we examined 1 and 9 month old Pkd2+/- mice to determine if decreased amounts of functional polycystin 2 leads to impaired cardiac function with aging. …”
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657
GSK343 treatment decreased <i>in vivo</i> tumor volume and growth.
Published 2021“…Tumor volumes were monitored three times per week. (A) Animals treated with GSK343 had significantly decreased fold change in tumor volumes compared to mice treated with vehicle. …”
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658
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659
Earlier Migration Timing, Decreasing Phenotypic Variation, and Biocomplexity in Multiple Salmonid Species
Published 2013“…<div><p>Climate-induced phenological shifts can influence population, evolutionary, and ecological dynamics, but our understanding of these phenomena is hampered by a lack of long-term demographic data. We use a multi-decade census of 5 salmonid species representing 14 life histories in a warming Alaskan stream to address the following key questions about climate change and phenology: How consistent are temporal patterns and drivers of phenology for similar species and alternative life histories? …”
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660
SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue
Published 2018“…Here, we show that the Nef protein of the highly divergent SIVcol lineage infecting mantled guerezas (<i>Colobus guereza</i>) is a potent antagonist of SERINC5, although it lacks the CD4, CD3 and CD28 down-modulation activities exerted by other primate lentiviral Nefs. …”