Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Positional cloning of <i>qNN1</i> on chromosome 16. by Xinxin Li (281237)

WT data of set A398E/V and set M1425V/I pooled for better comparison. by Yousra El Ghaleb (22075892)

Subjects:

Decreased hyper-resection in a NuA4 acetylation defective mutant in G1 and defect in DNA break repair by SSA. by Salar Ahmad (11457776)

“…(F) The <i>esa1-ts</i> mutation leads to a decrease of DSB repair by resection-based single-strand annealing. …”

Deletion of <i>ERG251-A</i> but not <i>ERG251-B</i> leads to decreased filamentation. by Xin Zhou (54275)

Image_1_Prediabetes: Adherence to Nutrition Visits Decreases HbA1c in Children and Adolescents.tiff by Sadichchha Parajuli (11716967)

Pyrimidine nucleotides are decreased in hypoxia, while precursors accumulate. by Emily B. Cohen (9106088)

Foldases and holdases each decrease the level of unfolded protein. by Adam MR de Graff (9767829)

GSK343 decreased neuroblastoma viability, proliferation, and motility. by Laura V. Bownes (10276762)

“…<p>(A) SK-N-AS, SK-N-BE(2), SH-EP and WAC(2) cells (1.5 × 10³ cells) were treated with increasing concentrations of GSK343 (0, 5, 15, 25 μM) for 24 hours and viability was measured using alamarBlue^® assay. …”

MMR mutants show decreased mating-type silencing. by Qian Liu (135614)

“…<i>sir1Δ</i> mutant was used as a positive control. <b>(D)</b> Cells of indicated strains were 10-fold serially diluted and then spotted onto SC (left), SD-Ura (middle) and SC+FOA(right) agar plates, the <i>sir1Δ</i> mutant served as a positive control. …”

Bortezomib decreases osteoclasts and improves fracture repair in mice. by Hengwei Zhang (2397610)

Five-hours-old clots were subjected to scanning electron microscopy. by Jan Víteček (11434774)

Genes with a log2 fold-change > 5 in the LPS, IFNγ, LPS+IFNγ datasets not present in the IL-4 dataset. by Giorgia Colombo (6337118)

Three Ca_V3.3 variants left-shift the window current, while the A398V completely abolishes the window current. by Yousra El Ghaleb (22075892)

Subjects:

Number of significant genes and fold change. by Gordon A. Barr (11163243)

“…The effect of infant treatment on adult affective behavior showed a complex treatment by age dependent effect. Adult social behavior was decreased following Shock+mother pairings at both PN5-9 and PN10-14, whereas shock alone had no effect. …”

eIF5a is up-regulated in unruptured AAAs and decreased in ruptured AAAs. by Dong Ma (584680)

Subjects:

Inactivation of one allele of FT5. by Sophia Bigot (16469992)

DataSheet_1_Failure to decrease HbA1c levels following TB treatment is associated with elevated Th1/Th17 CD4+ responses.pdf by Robert Krause (504842)

“…</p>Results<p>CD62 P-selectin was up- (1.5-fold) and IL-10 downregulated (0.85-fold) in plasma among individuals whose HbA1c remained stable/increased during TB treatment. …”

Distinct effects on calcium channel activation of <i>CACNA1I</i> disease-associated amino acid substitutions A398E/V and M1425V/I. by Yousra El Ghaleb (22075892)

Subjects:

Transepithelial resistance of NHBE decreases significantly after PAA exposure. by Ellie S. Burns (21246537)