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Decreased Pre-existing Ad5 Capsid and Ad35 Neutralizing Antibodies Increase HIV-1 Infection Risk in the Step Trial Independent of Vaccination
Published 2012“…<div><h3>Background</h3><p>The Step trial raised the possibility that uncircumcised men with pre-existing Ad5 neutralizing antibodies carried an increased risk of HIV infection after vaccination. …”
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Four-fold decrease in [H<sup>+</sup>]<sub>e</sub> shifted GLT-1a E<sub>rev</sub> by −18 mV at both low and high glutamate concentrations.
Published 2015“…Arrows show GLT-1a E<sub>rev</sub> shifts. <b>(C)</b> Average GLT-1 E<sub>rev</sub> shifts at 37.5 μM and 600 μM are approximately equal when [H<sup>+</sup>]<sub>e</sub> was decreased from 40 to 10 nM.…”
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Four-fold decrease in [K<sup>+</sup>]<sub>e</sub> shifted GLT-1a E<sub>rev</sub> by +22 mV at both low and high glutamate concentrations.
Published 2015“…Arrows show GLT-1a E<sub>rev</sub> shifts. <b>(C)</b> Average GLT-1 E<sub>rev</sub> shifts at 37.5 μM and 600 μM are approximately equal when [K<sup>+</sup>]<sub>e</sub> was decreased from 44 to 11 mM.…”