Showing 201 - 220 results of 104,129 for search '(( a fold decrease ) OR ( 5 ((((step decrease) OR (nn decrease))) OR (a decrease)) ))', query time: 1.21s Refine Results
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    Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa by Andrej Emanuel Cotman (5203904)

    Published 2023
    “…Starting from DNA gyrase inhibitor <b>1</b>, we identified compound <b>27</b>, featuring a 10-fold improved aqueous solubility, a 10-fold improved inhibition of topoisomerase IV from A. baumannii and P. aeruginosa, a 10-fold decreased inhibition of human topoisomerase IIα, and no cross-resistance to novobiocin. …”
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    Depletion of SNEV decreases the splicing efficiency of nuclear extracts by Johannes Grillari (13055)

    Published 2011
    “…Lane 1 shows the unspliced adenoviral pre-mRNA. A decrease of the second catalytical step of the reaction was observed in the SNEV depleted extracts when compared to depleted controls, where irrelevant antibodies were used for depletion (lanes 3 and 4) or where untreated NE was used for splicing (lane 2). …”
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    GSK343 decreased neuroblastoma viability, proliferation, and motility. by Laura V. Bownes (10276762)

    Published 2021
    “…<p>(A) SK-N-AS, SK-N-BE(2), SH-EP and WAC(2) cells (1.5 × 10<sup>3</sup> cells) were treated with increasing concentrations of GSK343 (0, 5, 15, 25 μM) for 24 hours and viability was measured using alamarBlue<sup>®</sup> assay. …”
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    MMR mutants show decreased mating-type silencing. by Qian Liu (135614)

    Published 2020
    “…<i>sir1Δ</i> mutant was used as a positive control. <b>(D)</b> Cells of indicated strains were 10-fold serially diluted and then spotted onto SC (left), SD-Ura (middle) and SC+FOA(right) agar plates, the <i>sir1Δ</i> mutant served as a positive control. …”
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