Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Argon-mediated decrease of apoptosis is attenuated following ERK1/2 and TLR inhibition. by Felix Ulbrich (678720)

Decrease of NF-κB activity in tumor tissue of CCR5^−/− mice. by Ju Kyoung Song (324058)

“…<p><b>A</b>, The DNA binding activity of NF-κB was determined in the nuclear extracts of the CCR5^−/− mice and CCR5^+/+ mice tumor tissues by EMSA described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033747#s4" target="_blank">material and methods</a>. …”

Locomotion and anxiety-like behavior of GIRK2^WT and GIRK2^AgRP-KO mice. by Youjin Oh (3308670)

Decreased processivity of A3G NPM was attributable to changes in sliding, but not jumping movements. by Anjuman Ara (540372)

Decreased diaphragm muscle lateral bifurcations in GAD67-deficient (−/−) E15.5 mice. by Matthew J. Fogarty (283288)

“…<b>D</b> shows a significantly decreased lateral bifurcation number but not medial bifurcation (mean ± SEM) in GAD67-deficient mice compared to wild type (<i>n</i> = 5, *<i>P</i><0.05, unpaired <i>t</i> test). …”

Overexpression of Tdp2 was associated with a decrease in HBV CCC DNA. by Xiuji Cui (755449)

Rictor deletion leads to a decrease in B cells in the PB and spleen. by Yingchi Zhang (607489)

Regulation of skin γδ T cell proliferation by glucose is associated with decreased STAT5B phosphorylation. by Kristen R. Taylor (246328)

Hypoxia decreases expression of AQP5 protein and mRNA levels in MLE-12 cells. by Jitesh D. Kawedia (384551)

FABP5 down regulation increases inflammation but decreases innate immunity in primary NHBE cells. by Fabienne Gally (260470)

“…<p><b>A.</b> CS exposure increases <i>P. aeruginosa</i> colony forming units (CFU) on FABP5 knocked down primary NHBE cells. …”

si-AGR2 decreased DNP-mediated invasion and motility in 5–8F cells. by Yuejin Li (410414)

Deletion of <i>VdSep5</i> decreased secretory protein delivery to the hyphal neck. by Ting-Ting Zhou (2236807)

RSV decreased the Cav-1 and TGF-β expression in liver of rats fed high-fat diet. by Hui Yang (91136)

Revisiting the sealed heating method–heating cells in a low volume decreases nuclear Chk1. by Andrew J. Massey (239469)

Mitochondrial protein acetylation correlates with a decrease in sirtuin 3 levels. by Mercedes García-Roche (6459200)

Glucocorticoid receptor knockdown is associated with a decrease in nuclear Nrf2. by Elena Obrador (559979)

Disruption of putative host factor LGMN decreases SARS-CoV-2 viral entry. by Ravi K. Dinesh (21736629)

DNA methylation of RALBP1 is associated with a decrease in gene expression. by Tina Rönn (253292)

“…<p>A CpG site in the promoter region of <i>RALBP1</i> showed A) increased DNA methylation in response to exercise as well as B) a decrease in mRNA expression. …”