Showing 12,001 - 12,020 results of 105,498 for search '(( a fold decrease ) OR ( 5 ((nn decrease) OR (((mean decrease) OR (a decrease)))) ))', query time: 1.12s Refine Results
  1. 12001

    Image_5_Myricetin, the Main Flavonoid in Syzygium cumini Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5.tif by Renato Simões Gaspar (8384040)

    Published 2020
    “…Additionally, myricetin is a novel inhibitor of ERp5 and PDI, unveiling a new therapeutic perspective for the treatment of thrombotic disorders.…”
  2. 12002

    Image_5_Myricetin, the Main Flavonoid in Syzygium cumini Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5.tif by Renato Simões Gaspar (8384040)

    Published 2020
    “…Additionally, myricetin is a novel inhibitor of ERp5 and PDI, unveiling a new therapeutic perspective for the treatment of thrombotic disorders.…”
  3. 12003

    Table_5_Two DNA Methyltransferases for Site-Specific 6mA and 5mC DNA Modification in Xanthomonas euvesicatoria.XLSX by Hye-Jee Park (3594245)

    Published 2021
    “…Xe(XvDMT2) was more tolerant to EtOH than Xe(XvDMT1), which had enhanced tolerance to sorbitol but decreased tolerance to polymyxin B. Using single-molecule real-time sequencing and methylation-sensitive restriction enzymes, we successfully predicted putative motifs methylated by XvDMT1 and XvDMT2, which are previously uncharacterized 6mA and 5mC DNA MTases, respectively. …”
  4. 12004
  5. 12005
  6. 12006
  7. 12007
  8. 12008
  9. 12009

    DataSheet_1_Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models.pdf by Emilia J. Berthold (13839388)

    Published 2022
    “…</p>Results<p>Both CsA and ALV robustly inhibited viral replication in all models; both compounds decreased HCoV-229E RNA in phBECs and reduced luminescence in HCoV-229E-RLuc-infected Huh7.5 and SARS-CoV-1-RLuc replicon-transfected HEK293. …”
  10. 12010
  11. 12011
  12. 12012

    Additional file 6 of ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy by Lihong Lu (10532648)

    Published 2021
    “…(D) Compared with the control group, the mRNAexpression of KMT5A was decreased in aortic tissues of DN rats. (* p < 0.05,** p < 0.01, *** p < 0.001, **** p < 0.0001, n = 10/group).…”
  13. 12013

    m<sup>6</sup>A mRNA methylation controls autophagy and adipogenesis by targeting <i>Atg5</i> and <i>Atg7</i> by Xinxia Wang (301455)

    Published 2019
    “…Mechanistically, knockdown of FTO, a well-known m<sup>6</sup>A demethylase, decreased the expression of ATG5 and ATG7, leading to attenuation of autophagosome formation, thereby inhibiting autophagy and adipogenesis. …”
  14. 12014

    The <i>sf3b1-698</i> mutants are defective in fecundity and lifespan. by Bei Zhang (428038)

    Published 2021
    “…Females of the two sf3b1 mutants laid no significantly changed eggs during the late half of test time. Means: WT = 175, H698D = 195.5, p = 0.5296, H698R = 173.4, p = 0.9437. …”
  15. 12015
  16. 12016

    Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer by Hong Im Kim (4686187)

    Published 2022
    “…Spermidine is required for the hypusine-dependent activation of eukaryotic translation initiation factors 5A1 (eIF5A1) and 5A2 (eIF5A2) and connects the MYC/ODC-induced deregulation of spermidine to eIF5A1/2 protein translation, which is increased during cancer cell proliferation. …”
  17. 12017

    Data_Sheet_1_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.DOCX by Ai Qing Yu (9774356)

    Published 2021
    “…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”
  18. 12018

    Data_Sheet_2_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLS by Ai Qing Yu (9774356)

    Published 2021
    “…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”
  19. 12019

    Data_Sheet_3_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLSX by Ai Qing Yu (9774356)

    Published 2021
    “…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”
  20. 12020

    A new resource allocation model partitions the genome in five expression sectors. by Mónica Chagoyen (4253800)

    Published 2019
    “…<p><b>A)</b> Top. Resource allocation model (Model 1) based on three sectors in which the expression of their constituent genes increases (positive genes, blue), decreases (negative genes, red), or remains constant (invariant genes, brown) with increasing growth rate. …”