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543
A New Rotane Family: Synthesis, Structure, Conformation, and Dynamics of [3.4]-, [4.4]-, [5.4]-, and [6.4]Rotane<sup>1</sup>
Published 1998“…At the same time their folding decreases, until in <b>8</b> they are close to planar. …”
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544
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545
Forty-two receptors arranged in order of decreasing interaction with the full set of thirty-five drugs.
Published 2010“…<p>The forty-two receptors are arranged in order of decreasing interaction with the full set of thirty-five drugs, based on the breadth statistics, B, B<sub>sq</sub>. and B<sub>exp</sub>. …”
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546
Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”
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547
Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”
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548
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549
Decrease of NF-κB activity in tumor tissue of CCR5<sup>−/−</sup> mice.
Published 2013“…<p><b>A</b>, The DNA binding activity of NF-κB was determined in the nuclear extracts of the CCR5<sup>−/−</sup> mice and CCR5<sup>+/+</sup> mice tumor tissues by EMSA described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033747#s4" target="_blank">material and methods</a>. …”
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550
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551
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552
Decreased diaphragm muscle lateral bifurcations in GAD67-deficient (−/−) E15.5 mice.
Published 2013“…<b>D</b> shows a significantly decreased lateral bifurcation number but not medial bifurcation (mean ± SEM) in GAD67-deficient mice compared to wild type (<i>n</i> = 5, *<i>P</i><0.05, unpaired <i>t</i> test). …”
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553
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554
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555
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557
FABP5 down regulation increases inflammation but decreases innate immunity in primary NHBE cells.
Published 2013“…<p><b>A.</b> CS exposure increases <i>P. aeruginosa</i> colony forming units (CFU) on FABP5 knocked down primary NHBE cells. …”
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558
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559
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560