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HRMECs treated with 3-Deazaneplanocin A (DZNep) chemical inhibitor demonstrated increased miR-200b and decreased VEGF expression.
Published 2015“…[NG = 5mM D-glucose, HG = 25mM D-glucose, NG+DMSO = 5mM D-glucose + 0.05% DMSO, HG+DMSO = 25mM D-glucose + 0.05% DMSO, NG+DZNEP = 5mM D-glucose + 5μM DZNep, HG+DZNEP = 25mM + 5μM DZNep; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to β-actin for VEGF and U6 for miR-200b, expressed as a fold change of NG].…”
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A PPARα Promoter Variant Impairs ERR-Dependent Transactivation and Decreases Mortality after Acute Coronary Ischemia in Patients with Diabetes
Published 2010“…<em>PPARA</em> A for both ERR-α and -γ (3.1 vs.1.9-fold; P<0.05). …”
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Analysis of Drugs in Whole Blood by Paper Spray Mass Spectrometry with Integrated Solid-Phase Extraction
Published 2025“…The detection limits were at single digit or subng/mL levels or lower for all analytes for 70 μL blood sample, with a median decrease of 9-fold compared to paper spray without SPE.…”
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TUDCA decreases MPO with improved mitochondrial biogenesis, mitochondria-ER contact, and alveolar formation of HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The increased MPO levels in HOX neonatal lungs are decreased by TUDCA treatment (0.1±0.1-fold; n = 6, p<0.05). …”
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Pharmacodynamic Profile of CCX168 in Healthy Human Volunteers.
Published 2016“…CD11b upregulation was diminished in both blood samples from CCX168 subjects with a 10-fold decrease in C5a potency exhibited in the 12-hour samples.…”
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Cytosolic mitochondrial DNA release upon MeV and MeV-ΔV infection in culture and in mice.
Published 2023Subjects: -
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