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781
Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41
Published 2011“…Resistance to neutralization by 2F5 and 4E10 was observed with Nef from a diverse range of HIV-1 and SIV isolates, as well as with HIV-1 virions bearing Env from CCR5- and CXCR4-tropic viruses, clade B and C viruses, or primary isolates. …”
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782
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783
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784
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785
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786
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787
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788
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789
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790
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791
Allelic loss of <i>Cdh11</i> led to faster growing tumors due to decreased cell death.
Published 2010“…<p>(A) The number of single tumor initiating cells at PND8 was estimated by averaging the total number of TAg-positive cells in 5 mice per genotype. …”
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792
Proinflammatory signaling pathways were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters.
Published 2022“…<p><b>(A)</b> Boxplots of SARS-CoV-2 transcripts normalized read counts across all animals, vaccinated hamsters are shown in blue and pink, and sham animals in green. …”
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793
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794
PDGF-BB maintains Bcl2/Bax ratio and decreases caspase-3 activation induced by Tat and morphine.
Published 2011“…(B) Densitometric analysis of the blots shown in (A). Tat and morphine together resulted in a significantly decreased ratio of Bcl2/Bax, indicating cell's progress towards apoptosis. …”
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795
Decreasing ShcA expression enhances TGF-β-induced Smad signaling.
Published 2015“…Note the enhanced basal pSmad3 or pSmad2 levels in cells transfected with ShcA siRNA. ShcA immunoblotting reveals decreased ShcA levels in cells transfected with ShcA siRNA, and GAPDH immunoblotting serves as loading control. …”
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796
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797
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798
Loss of Pcgf5 results in reduction in global H2AK119 levels.
Published 2016“…<p>(A) H2AK119ub1 levels in LK cells. LK cells from BM of WT and <i>Pcgf5</i><sup><i>Δ/Δ</i></sup> mice were analyzed by Western blotting using anti-H2AK119ub1 and anti-H3K27me3 antibodies at 1-month post deletion of <i>Pcgf5</i>. …”
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799
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800