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Tacrolimus Decreases Albuminuria in Patients with IgA Nephropathy and Normal Blood Pressure: A Double-Blind Randomized Controlled Trial of Efficacy of Tacrolimus on IgA Nephropathy
Published 2013“…We randomly assigned patients either to receive tacrolimus or placebo with stratification by using a renin angiotensin system blocker. …”
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323
Neural networks classify states which differ in neuronal activity levels using ensembles of neurons that increase/decrease their activity in each state.
Published 2021“…As a result, there is an increase (neurons 51:100) or decrease (neurons 1:50) in activity levels in State B compared to State A. …”
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324
Non-Pneumatic Anti-Shock Garment (NASG), a First-Aid Device to Decrease Maternal Mortality from Obstetric Hemorrhage: A Cluster Randomized Trial
Published 2013“…We hypothesized the NASG group would have a 50% reduction in adverse outcomes.…”
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325
The decrease of C/EBPα protein during apoptosis involves induction of protein degradation and inhibition of transcription.
Published 2009“…Then, C/EBPα protein was detected with β-actin as a loading control. Folds of decrease of C/EBPα protein/β-actin ratios against untreated cells are shown as means±SD of three independent experiments. …”
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326
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Structural Alterations of the “Address” Moiety of NAN Leading to the Discovery of a Novel Opioid Receptor Modulator with Reduced hERG Toxicity
Published 2023“…Follow-up hERG channel inhibition evaluation revealed a seven-fold decreased potency of compound <b>21</b> compared to NAN. …”
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Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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331
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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332
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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333
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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334
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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335
Response of small airway tissues infected with EV-D94 and decreasing doses of EV-D68.
Published 2022“…<p>Tissues were infected with 1E7 RNA copies of EV-D94 (equivalent to 2,46E4 TCID50) and 1E7 RNA copies of EV-D68 (3,3E5 TCID50) as well as decreasing doses of the latter. …”
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336
Different Association of Human Papillomavirus 16 Variants with Early and Late Presentation of Cervical Cancer
Published 2016“…Only the D2 variant conferred a 3.3-fold increase in the risk of developing CC before 50 years of age (OR = 3.3, 95% CI = 1.7–6.6, p < 0.001) in relation with non-HPV16 cases. …”
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