AMPs are increased in lesional HS, but DCD and other sweat-gland associated proteins are decreased. by Margaret Coates (6058580)

“…<p>(A) Volcano plot showing increased or decreased genes in HS. …”

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. by Kevin Yuswan (19845885)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Decreased expression of Rho in the <i>nrl</i>-KO retinas as detected by dot blotting. by Fei Liu (21082)

Treatment with TDF decreased cell viability and induced morphological changes in hepatic stellate cells. by Sung Won Lee (222509)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. …”

Conditional ablation of <i>Ybx1</i> leads to a reduction in cortical progenitor cell pool and a decrease in cortical thickness. by Jian Zhang (1682)

Thermal denaturation of ZIKV NS2B/NS3^pro and CHIKV nsP2^pro using fluorescence spectroscopy. by Raphael J. Eberle (9286932)

Analysis of sphingosine levels from BAL. by Henning Carstens (13132801)

Drugs susceptibility profile (EC₅₀ values and Fold-change) to the antileishmanials in all polyene resistant lines of <i>Leishmania</i> spp. by Edubiel A. Alpizar-Sosa (13848145)

“…Values higher and lower than 1, indicate a decrease and increase in susceptibility, respectively.…”

Image_1_Desmoglein-4 Deficiency Exacerbates Psoriasiform Dermatitis in Rats While Psoriasis Patients Displayed a Decreased Gene Expression of DSG4.TIF by Tamara Moreno-Sosa (10717320)

Image_2_Desmoglein-4 Deficiency Exacerbates Psoriasiform Dermatitis in Rats While Psoriasis Patients Displayed a Decreased Gene Expression of DSG4.TIF by Tamara Moreno-Sosa (10717320)

Genes whose expression was decreased by 1 mM ouabain by more than 2-fold. by Larisa V. Smolyaninova (3600053)

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…Anthropogenic activities, particularly land use change and management practices, alter the global nitrogen (N) cycle. As a central part of the global N cycle, soil N supply from net N mineralization (NNM) and net nitrification (NN) contributes to over 50% of crop N uptake. …”

Detailed meta–analyses in untreated hypothyroid patients compared with controls for each HRV parameters: RR intervals, SDNN, RMSSD, pNN50, TP, LF, HF, LF/HF. by Valentin Brusseau (12769704)

Variable importance plot (mean decrease accuracy and mean decrease Gini). by Fernando Martinez-Taboada (8655132)

Survivability is decreased in zebrafish embryos following exogenous treatment with an amino-terminal fragment of nApoE4_1-151. by Madyson M. McCarthy (9238322)

Chronic high glucose induces apoptosis and proteasome activities decrease in INS-1E cells. by Christophe Broca (538652)

The <i>rcan-1</i> rearrangement allele decreases expression of <i>rcan-1</i>. by Yuehui Zhao (3146229)

“…The gene with the largest and most significant expression decrease was <i>rcan-1</i>. Red: p<0.01, log₂(Fold Change) > 1. …”