Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... by Saeid Safiri (3713035)

“…In 2019, Monaco had the highest age-standardised incidence rate (31.9 cases (23.3 to 56.9) per 100 000), while Lebanon had the highest age-standardised death rate (10.4 (8.1 to 13.7)). …”

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 by Hedyeh Ebrahimi (7321358)

“…Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …”

A new concept to achieve optimal weight gain in malnourished infants on total parenteral nutrition by Abi Nader, Elie

“…Optimal weight gain during nutrition rehabilitation should occur at the velocity of statural age (adjusted to the 50th percentile of height) and not chronological age. …”
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Impact of timing and severity of COVID-19 infection in pregnancy on intrauterine fetal growth- a registry-based study from Doha-Qatar by Fathima Minisha (16475100)

“…<h3>Background</h3> <p>The novel coronavirus disease (COVID-19) pandemic has impacted pregnant women, increasing maternal and neonatal morbidity. The placenta is a potential target for the pathophysiological processes due to the increased thrombotic inflammatory activation and inadequate uteroplacental perfusion and oxygenation, potentially causing intrauterine growth restriction. …”

Obesity as a risk factor for sedation-related complications during propofol-mediated sedation for advanced endoscopic procedures by Azar, Riad

“…Increasing BMI was associated with an increased frequency of AMs (BMI <30, 10.5%; 30-35, 18.9%; >35–26.8%; P < .001) and hypoxemia (BMI <30, 5.3%; 30-35, 9.4%; >35, 13.4%; P = .001); there was no difference in the frequency of need for vasopressors (P = .254) and premature termination of procedures (P = .401). …”
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In‐hospital neonatal mortality and the role of consanguinity by Matar, Maroun

“…The rate of first cousin marriage was 9.9%. Consanguinity was significantly associated with in‐hospital mortality (odds ratio 2.4; 95% confidence interval (CI): 1.8, 3.1); consanguinity remained a significant predictor of mortality (odds ratio 1.8 [95% CI: 1.2, 2.9]) after adjusting for maternal age and education, crowding index, history of abortion, prenatal care, mode of delivery, gender, birthweight and apgar score at 5 minutes. …”
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Peroneal tendon dislocation in talus fracture and diagnostic value of fleck sign by Ahmed Khalil Attia (10334814)

“…Patient records were reviewed for laterality, age, sex, mode of injury, associated injuries and operative interventions. 50 ankles met the inclusion criteria. 49 were males, mean age was 32.5 year and the predominant mode of injury was a fall from height.…”

Voiding function improves under long-term testosterone treatment (TTh) in hypogonadal men, independent of prostate size by Aksam Yassin (14779204)

“…</p><h3>Patients and methods</h3><p dir="ltr">In this study 321 hypogonadal patients with an average age of 58.9 ± 9.52 years received testosterone undecanoate in 12-week intervals for 12 years. …”

Extra-articular Tenodesis for ACL Reconstruction: Who Needs it and is there a Superior Technique? by Enejd Veizi (23653423)

“…Optimal results depend on appropriate indications, careful technique, and tailoring the approach to patient factors such as age, sport demands, laxity profile, and skeletal maturity.…”

Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …”
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Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes by Sassi, Yassine

“…MRP4-deficient mice displayed enhanced cardiac myocyte cAMP formation, contractility, and cardiac hypertrophy at 9 mo of age, an effect that was compensated transiently by increased phosphodiesterase expression at young age. …”
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Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation by Larissa Haertle (3864310)

“…In view of the increased risk of developing AD in T21 individuals, we additionally investigated the T21-associated sites in published blood DNA methylation data from the AgeCoDe cohort (German study on Ageing, Cognition, and Dementia). …”

Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance by Zouhaier Farhani (22330693)

“…Continuous bout duration showed a greater (<i>p</i> < 0.05) percentage of successful passes compared to 2 × 6 min (4vs4; <i>d</i> = 2.57 [very large] and 3vs3: <i>d</i> = 1.79 [large]) and 3 × 4 min (4vs4: <i>d</i> = 2.14 [very large] and 3vs3; <i>d</i> = 1.73 [large]). …”

Distribution and predictors of emergency department charges by Dimassi, Hani

“…While greater than 80 % of visit charges went to physician and facility fee for low acuity cases, these contributed to only 52 and 54 % of the high acuity presentations where ancillary services and solutions’ contribution to the total charges increased. The total charges for males were $14 higher than females; age was a predictor of higher charges with total charges of patients greater than 60 years of age being around $113 higher than ages 0–18 after controlling for all other variables. …”
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Patterns of pain medication use in older individuals with cardiovascular disease by Kabbara, Wissam K.

“…Background: Pain is common in older adults and clinicians are often faced by many challenges when selecting appropriate treatment due to age-related changes in pharmacokinetics, pharmacodynamics, increased comorbidities, and polypharmacy. …”
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Artificial Intelligence (AI) based machine learning models predict glucose variability and hypoglycaemia risk in patients with type 2 diabetes on a multiple drug regimen who fast d... by Tarik Elhadd (5480393)

“…</p><h3>Results</h3><p dir="ltr">The median age of participants was 51 years (IQR 49–52); median BMI was 33.2 kg/m² (IQR 33.0–35.9) and median HbA1c was 7.3% (IQR 6.7–7.8). …”

The global, regional, and national burden of pancreatic cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global B... by Akram Pourshams (63963)

“…</p><p><br></p><h3>Findings</h3><p dir="ltr">In 2017, there were 448 000 (95% UI 439 000–456 000) incident cases of pancreatic cancer globally, of which 232 000 (210 000–221 000; 51·9%) were in males. The age-standardised incidence rate was 5·0 (4·9–5·1) per 100 000 person-years in 1990 and increased to 5·7 (5·6–5·8) per 100 000 person-years in 2017. …”

Prevalence and factors associated with falls in older adults in a Middle Eastern population: a retrospective cross-sectional study by D.A. Alsayed Hassan (19724410)

“…The prevalence of falls was 6.7% (95% CI 6.6–6.9). Compared to individuals aged 60–69 years, individuals aged 70–79, 80–89, and 90–99 had increased odds of falls by 1.6 (95% CI 1.5, 1.8), 2.5 (95% CI 2.2, 2.8), and 2.6 (95% CI 2.0, 3.3), respectively. …”

Diagnosing type 2 diabetes using Hemoglobin A1c: a systematic review and meta-analysis of the diagnostic cutpoint based on microvascular complications by Alexandra E. Butler (6189536)

“…</p><h3>Conclusions</h3><p dir="ltr">The prevalence of nephropathy and moderate retinopathy was increased in subjects with HbA1c values ≥ 6.5% confirming the high specificity of this value for diagnosing T2DM; however, at HbA1c < 6.5% retinopathy increased at age > 55 years and, most strikingly, in African-Americans, suggesting there may be excess microvascular complication prevalence (particularly nephropathy) in individuals below the diabetes diagnostic threshold.…”

Chromogranin A‐positive hormone‐negative endocrine cells in pancreas in human pregnancy by Abu Saleh Md Moin (6189512)

“…</p> <h2>Methods</h2> <p>Autopsy pancreata from pregnant women (<em>n</em> = 14) and age-matched non-pregnant control women (<em>n</em> = 9) were obtained. …”