بدائل البحث:
age increased » _ increased (توسيع البحث)
a large » _ large (توسيع البحث)
decrease » increase (توسيع البحث)
age increased » _ increased (توسيع البحث)
a large » _ large (توسيع البحث)
decrease » increase (توسيع البحث)
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1
Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
منشور في 2020"…<p dir="ltr">In somatic cells/tissues, methylation of ribosomal DNA (rDNA) increases with age and age‐related pathologies, which has a direct impact on the regulation of nucleolar activity and cellular metabolism. …"
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2
Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
منشور في 2018"…<div><p>Increased cell senescence contributes to the pathogenesis of aging and aging-related disease. …"
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4
A clustering metaheuristic for large orienteering problems
منشور في 2022"…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …"
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5
Deep aging clocks: AI-powered strategies for biological age estimation
منشور في 2025"…<p>Several strategies have emerged lately in response to the rapid increase in the aging population to enhance health and life span and manage aging challenges. …"
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6
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a Bayesian hierarchical cohort component model that analysed estimated age-specific fertility and mortality rates along with 1250 censuses and 747 population registry years. …"
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7
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. Our findings suggest that direct activation of GLP-1R by Ex-4 reduces OA-induced steatosis in HepG2 cells by reducing fatty acid uptake and transport via FABP1 downregulation.…"
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8
A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
منشور في 2021"…To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …"
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9
Aging Effects in Field-Compacted Dredged Material
منشور في 2013"…This paper contains the results of aging study performed on 365-day-old trial highway embankments constructed of field-compacted dredged material (DM), steel slag fines (SSF), and three DM-SSF blends. …"
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11
Perinatal factors impacting echocardiographic left ventricular measurement in small for gestational age infants: a prospective cohort study
منشور في 2023"…<h2>Introduction</h2><p dir="ltr">Infants born small for gestational age (SGA) have an increased risk of developing various cardiovascular complications. …"
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12
When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial
منشور في 2021"…Univariate analysis showed a significant increase in the frequency of epileptogenic lesions with decreasing age, the presence of developmental delay, and the number and types of seizures at presentation. …"
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13
Over‐the‐counter access to emergency contraception without age restriction
منشور في 2013"…Family planning remains a high priority area for the United States, with goals to increase the proportion of pregnancies that are intended, reduce pregnancy rates among adolescents, and increase contraceptive use prioritized in the Healthy People 2020 objectives. …"
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14
Phosphorus supplementation increases thermic response to glucose solution in healthy lean subjects
منشور في 2013"…We hypothesised that the addition of P to a glucose load would enhance ATP production resulting in an increase in TEF. To test this hypothesis, we measured the TEF of glucose solution with or without P in seven healthy subjects (3M 4F; Age=21.1±0.8y; BMI= 23.2 ±1.3kg/m2) in a cross over design with 1 week washout period. …"
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15
Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
منشور في 2021"…Objective: Normal aging is often associated with cognitive deterioration in older adults, but the prevalence of cognitive decline like cognitive impairment, Alzheimer’s disease and dementia has been increasing lately. …"
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masterThesis -
16
Health Care Accessibility of Lebanese Working-Age Adults with Musculoskeletal Disability
منشور في 2016"…The diversity of the Lebanese society increased after the 1975-1990 civil war, the grapes of Wrath conflict and July 2006 war. …"
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17
Crisis Management and Crisis Communication in the Digital Age: The Impact of Social Media
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doctoralThesis -
18
Young bone marrow transplantation delays bone aging in old mice
منشور في 2025"…However, the specific involvement of bone marrow (BM) or hematopoietic cells in producing such factors and their effects on aging is still unclear. We developed a model of aged mice with transplanted young or old BM cells and assessed the impact on the aging process, specifically on energy metabolism and bone remodeling parameters. …"
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19
Effect of consanguinity on birth weight for gestational age in a developing country
منشور في 2007"…Birth weight was modeled by use of the fetal growth ratio, defined as the ratio of the observed birth weight to the median birth weight for gestational age. A mixed-effect multiple linear regression model was used to predict the net effect of first- and second-cousin marriage on the birth weight for gestational age, accounting for within-hospital clustering of data. …"
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20
Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism
منشور في 2023"…<p dir="ltr">Children from old fathers carry an increased risk for autism spectrum (ASD) and other neurodevelopmental disorders, which may at least partially be mediated by paternal age effects on the sperm epigenome. …"