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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. Our findings suggest that direct activation of GLP-1R by Ex-4 reduces OA-induced steatosis in HepG2 cells by reducing fatty acid uptake and transport via FABP1 downregulation.…”
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …”
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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. Male and female KO and WT mice were fed a HF diet (45% kcal fat) for 16 weeks. …”
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The new accounting standard IFRS 9 and its impact on how banks should provision for credit losses
Published 2019“…IFRS9 also can affect deal pricing under the new standard for risky customers may get higher price than normal customers. …”
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Genetic engineering to enhance microalgal-based produced water treatment with emphasis on CRISPR/Cas9: A review
Published 2023“…Bioremediation using microalgae has received increased interest as a method for produced water treatment for removing not only major contaminants such as nitrogen and phosphorus, but also heavy metals and hydrocarbons. …”
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Shear Strength Behaviors of Tire Shred-Dune Sand Admixtures
Published 2024Get full text
doctoralThesis -
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Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation
Published 2021“…Mean ± standard deviation values at the distal femur at 8 weeks were 9.0 ± 2.5 vs. 7.0 ± 1.5 (p = 0.002) and at 52 weeks were 15.8 ± 9.5 vs. 8.5 ± 4.2 (p = 0.002). …”
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Comparing WZB117-liposome Synthesis via Thin-film Hydration and Microfluidic Methods
Published 2025Get full text
doctoralThesis -
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Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors
Published 2022“…Pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, also binds to Sox9 and results in a similar increase in pancreatic development markers. …”
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
Published 2013Get full text
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Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches
Published 2024“…In addition, the optimized SEC in this study is 14.5 % to 38.6 % lower than those reported in the literature. At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”
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