How Do Molecular Crowders Influence Ligand Binding Kinetics with G‑Quadruplex DNA? The Role of Bound Water حسب Parvez Alam (789093)

"…Understanding the kinetics of ligand interaction with G-quadruplex DNA (GqDNA) in a crowded cell-like environment is of paramount importance in biology and pharmacology, as it elucidates the effect of molecular crowders on reaction rates governing these interactionsa process that largely remains unexplored. …"

How Do Molecular Crowders Influence Ligand Binding Kinetics with G‑Quadruplex DNA? The Role of Bound Water حسب Parvez Alam (789093)

"…Understanding the kinetics of ligand interaction with G-quadruplex DNA (GqDNA) in a crowded cell-like environment is of paramount importance in biology and pharmacology, as it elucidates the effect of molecular crowders on reaction rates governing these interactionsa process that largely remains unexplored. …"

DYRK1A activity on HBV transcription regulatory regions. حسب Florentin Pastor (19852287)

Table 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx حسب Lili Zhou (265076)

"…</p>Methods<p>We retrospectively analyzed clinical data from 200 DLBCL patients and 185 healthy controls, focusing on lipid and lipoprotein levels, including triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), apolipoprotein A1 (ApoA1), apolipoprotein B (ApoB), and apolipoprotein E (ApoE). …"

Data Sheet 1_Impact of large-scale oceanic variability on Adriatic fisheries evidenced through the ‘mean temperature of the catch’ approach.docx حسب Elvis Kamberi (22759586)

Data Sheet 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx حسب Lili Zhou (265076)

"…</p>Methods<p>We retrospectively analyzed clinical data from 200 DLBCL patients and 185 healthy controls, focusing on lipid and lipoprotein levels, including triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), apolipoprotein A1 (ApoA1), apolipoprotein B (ApoB), and apolipoprotein E (ApoE). …"

Table 1_Association between excessive screen time and falls, with additional risk from insufficient sleep duration in children and adolescents, a large cross-sectional study in Chi... حسب Runquan Zhang (20393850)

YFV-Asibi NS4A-5 promotes replication of the cap0 virus. حسب Anja vom Hemdt (19787189)

الموضوعات:

Spectroscopic characterization of wild-type and p.R163C αB-crystallin: CD, FTIR and Raman analysis. حسب Aref Baharvand (21713886)

الموضوعات:

Translation efficiency of a replication-incompetent cap0 reporter YFV genome is reduced in mosquito cells. حسب Anja vom Hemdt (19787189)

الموضوعات:

Gene mapping, mass spectrometry, and purification of the wild-type and p.R163C mutant of human αB-crystallin. حسب Aref Baharvand (21713886)

الموضوعات:

Results of SD-TOPSIS application ‐ combinations C1-C10. حسب Roman Vavrek (13200141)

Region similarity and individual similarity across the three age groups: a) young (<30 years, b) middle-aged (≥30 & <60 years), and c) old age (≥60 years) for all cognitive systems... حسب Andrew Patton (10224161)

Translation efficiency of a replication-incompetent cap0 reporter YFV genome is reduced in Aag2 cells. حسب Anja vom Hemdt (19787189)

الموضوعات:

GPT-4 results in decreased error rate for all tasks with increasing complexity when compared to GPT-3.5-turbo. حسب Jacqueline A. Jansen (14894276)

Structural dynamics of wild-type and p.R163C mutant αB-crystallin dimers: insights from molecular simulations. حسب Aref Baharvand (21713886)

الموضوعات:

Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma حسب Hao Shi (158171)

"…</p> <p><b>Abbreviation</b>: 3-MA, 3-methyladenine; AL, autolysosome; AP, autophagosome; Baf-A1, bafilomycin A₁; BARA, β-α repeated autophagy specific domain; BH3, BCL2 homology 3 domain; CCD, coiled-coil domain; CHX, cycloheximide; Co-IP, co-immunoprecipitation; CQ, chloroquine; CTR, control; DAPI, 4′,6-diamidino-2-phenylindole; EBSS, Earle’s balanced salt solution; ECD, evolutionarily conserved domain; EEE, three-tyrosine phosphomimetic mutations Y229E Y233E Y352E; ER, endoplasmic reticulum; FFF, three-tyrosine non-phosphomimetic mutations; FFPE, formalin-fixed paraffin-embedded; FL, full-length; GIST, gastrointestinal stromal tumor; IB, immunoblotting; IHC, immunohistochemistry; KIT-HEK293, KIT stably expressing HEK293 cells; KRT20/CK20, keratin 20; LT, large T-antigen; LT339, MCPyV truncated LT antigen; LTco, codon-optimized MCPyV LT antigen; MCC, Merkel cell carcinoma; MCPyV⁻, MCPyV-negative; MCPyV, Merkel cell polyomavirus; MCPyV⁺, MCPyV-positive; PARP1, poly(ADP-ribose) polymerase 1; PCI, pan-caspase inhibitor; PI, propidium iodide; PtdIns3K, class III phosphatidylinositol 3-kinase; PtdIns3P, phosphatidylinositol-3-phosphate; RB1, RB transcriptional corepressor 1; RTKs, receptor tyrosine kinases; KITLG/SCF, KIT ligand; sT, small T-antigen; sTco, codon-optimized MCPyV sT antigen; T-B, Tat-BECN1; T-S, Tat-scrambled; TEM, transmission electron microscopy.…"

Association between flavonoid intakes and metabolic dysfunction-associated steatotic liver disease (MASLD) using a Restricted Cubic Spline regression model, adjusted for age, sex,... حسب Yuwei He (1565941)

Examples of the trash vessels in the study. حسب Ishana Shukla (20189612)

Estimated proportion of total sites occupied by invasive <i>Rattus</i>, followed by the detection probability. حسب Ishana Shukla (20189612)