Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”

Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”

Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”

Contribution of the through-mask leakages from the cavity and channel network distributed along the periphery of the mask; a–c and d–f are decreasing porosity <i>c</i><sub><i>k</i>... by Akshay Anand (118579)

Table 1_Association between excessive screen time and falls, with additional risk from insufficient sleep duration in children and adolescents, a large cross-sectional study in Chi... by Runquan Zhang (20393850)

Agreement with tolerance in the order of district towns in the results of SD-TOPSIS application in space ‐ combination A vs. B1. by Roman Vavrek (13200141)

Agreement with tolerance in the order of district towns in the results of SD-TOPSIS application in space ‐ combination A vs. D2. by Roman Vavrek (13200141)

Agreement with tolerance in the order of district towns in the results of SD-TOPSIS application in space ‐ combination A vs. C1. by Roman Vavrek (13200141)

Effect of SS-31 on mice lung tissue inflammation induced by BLM. by Quankuan Gu (20539301)

Fig 6 - by Keith Fraser (1868587)

Fig 7 - by Keith Fraser (1868587)

Modelled seroprevalence estimates (coloured regions) compared with real data (black). by Keith Fraser (1868587)

Effect of SS-31 on mice lung tissue inflammation induced by BLM. by Quankuan Gu (20539301)

Primers used for RT-PCR. by Quankuan Gu (20539301)

“…</p><p>Results</p><p>BLM caused a large decrease in body weight in mice. However, the intraperitoneal injection of SS-31 slowed down the body weight loss in the mice. …”

Table of parameters. by Keith Fraser (1868587)

Effect of SS-31 on apoptosis in lung tissues. by Quankuan Gu (20539301)

Pathological staining and the pathological score. by Quankuan Gu (20539301)

Effect of SS-31 on mouse body weight and inflammatory factors in serum. by Quankuan Gu (20539301)

Mitochondrial structural changes and oxidative stress. by Quankuan Gu (20539301)

Diagram of SEIRV model of yellow fever transmission in humans showing zoonotic transfer from the sylvatic non-human primate reservoir (mediated by the λ_<i>S</i> paramete... by Keith Fraser (1868587)