Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

Overview of the six original ACTIV-3/TICO trials. by Elizabeth S. Munroe (21568166)

Tissue, days post-infection (dpi) and the top 10 most significant genes with increased and decreased expression with valid gene symbols for the response contrasts. by Gillian P. McHugo (8965919)

IFN-γ and several PARP genes are upregulated in infected olfactory bulbs of JHMV infected mice. by Catherine M. Kerr (21492574)

GI-1d-a: Comparison of estimates of people for dataset A (left bar) and B (right bar) per region. The largest discrepancies occur in areas of NE, SE and SW Germany and adjacent reg... by Isabell Schmidt (6331013)

PARP9 knockdown promotes apoptosis and DNA damage. by Yating Li (1819822)

“…(E) DNA damage in GC cells significantly increased post-PARP9 knockdown as determined by comet assay. (F) The anti-DNA damage capacity of GC cells decreased markedly following reduction of PARP9 expression. …”

Innovation, nightlights and a continuous measure of city size. by Saul Estrin (8629173)

Selection frequencies plotted in decreasing order. by Hannah P. Rowe (7830599)

Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf by Maria Delgado-Ortet (8840702)

“…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…”

Trust change by gender. by Alain Abi-Rizk (8549358)

“…Results indicate that respondnatds from North America and Europe Experienced an increase in trust where as Africa and South America Witnessed a decline in trust. Males exhibited a greater decline in trust than females (p = 0.038), and undergraduate degree holders showed the largest decrease (p = 0.001). …”

Trust change by age group. by Alain Abi-Rizk (8549358)

“…Results indicate that respondnatds from North America and Europe Experienced an increase in trust where as Africa and South America Witnessed a decline in trust. Males exhibited a greater decline in trust than females (p = 0.038), and undergraduate degree holders showed the largest decrease (p = 0.001). …”

Trust change by education level. by Alain Abi-Rizk (8549358)

“…Results indicate that respondnatds from North America and Europe Experienced an increase in trust where as Africa and South America Witnessed a decline in trust. Males exhibited a greater decline in trust than females (p = 0.038), and undergraduate degree holders showed the largest decrease (p = 0.001). …”

Trust change by source of science information. by Alain Abi-Rizk (8549358)

“…Results indicate that respondnatds from North America and Europe Experienced an increase in trust where as Africa and South America Witnessed a decline in trust. Males exhibited a greater decline in trust than females (p = 0.038), and undergraduate degree holders showed the largest decrease (p = 0.001). …”

Trust levels before and after the COVID-19 pandemic (n = 10,000). by Alain Abi-Rizk (8549358)

Distribution of individual change in trust in science before and after the pandemic (n = 10,000). by Alain Abi-Rizk (8549358)

PARP cleavage analysis of sgCtrl and <i>IRF1</i> KO cells across conditions with and without vaccinia virus infection. by Tyron Chang (9922533)

Table 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.xlsx by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation by Anna Rutkowska (19676837)