Higher cellular A3G protein levels were associated with decreased infectivity and spread of HIV virions after <i>ex vivo</i> activation and infection of primary memory T lymphocyte... by MariaPia De Pasquale (471291)

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis. by Hiroyuki Mori (512656)

“…(<b>H</b>) Quantification of autoradiography for labeled TAG was by ImageJ. <i>n =</i> 5, data are mean ± SD. *<i>p</i> < 0.05. Uncropped western blots are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s016" target="_blank">S1 Raw Images</a>, and numerical data for all graphs are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s014" target="_blank">S6 Data</a>. …”

Effects of 5-HTR blockade on incentive. by Yukiko Hori (299784)

Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

Taste bud cell populations are decreased after <i>Sox2</i> deletion in epithelial stem/progenitor cells. by Makoto Ohmoto (3065106)

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-1 by Mrigank Srivastava (94935)

Inhibition of autophagic flux increases EtOH-induced oxidative stress, induces mitochondrial depolarization, and decreases cell viability. by Prasanna M. Chandramouleeswaran (3176268)

<i>S</i>. Typhimurium coordinates protein synthesis with protein folding capacity. by Carissa Chan (18310140)

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-4 by Mrigank Srivastava (94935)

The substitution F447L is adaptive for J4_S52-HVR1, while it decreases infectivity of parental J4 and J4_ΔHVR1 HCVcc. by Christina Holmboe Olesen (11154333)

Constitutive KIT activation in cells with gain-of function KIT mutations causes increased ROS levels and decreased DJ-1. by Do-Kyun Kim (2176492)

Genomic inactivation of the <i>PIWI</i> gene in <i>L. infantum</i> and <i>L. major</i> strains leads to a decrease in amastigote growth and disease pathology. by Prasad K. Padmanabhan (85254)

FABP5 expression levels in brain microvessels from 2-, 8-, 12-, and 24-month-old mice. by Takuro Iwao (14636741)

Subjects:

ChAT knock-down using an antisense oligodeoxynucleotide (AS-ODN) against ChAT, and decreased expression of ChAT in the DRG and spinal cord by Misaki Matsumoto (52354)

Reduced RabGEF1 expression decreases NGF-induced TrkA phosphorylation but not TrkA internalization. by See-Ying Tam (828866)

Inhibition of GLS1 decreases the proportion of CCR6 and CXCR3 expressing CD4⁺ T cells. by Zeynep Sener (3146064)

“…BPTES and 968 significantly decrease the proportion of CCR6 expressing cells under normoxia both at day 3 and 5, whereas 968 but not BPTES decrease the proportion of CCR6 expressing cells under hypoxia both at day 3 and 5. …”

Exposure to IQ3A compounds decreases <i>HSP90</i> and <i>KRAS</i> mRNA, protein expression and <i>KRAS</i> transcription. by Hugo Brito (747224)

Fraction of time, the overall of the studied data trends durations follow a geometric distribution with parameter <i>p</i> = 0.5, and with any <i>p</i>, both cases for a significan... by Héctor Raúl Olivares-Sánchez (13014866)

A decreased response to yeast odorant attractant is observed in <i>sema1a</i> knockdown animals. by Keshava Mysore (413368)