Cell viability in MPC (A) and MTT (B) cells: MPC and MTT cells were pre-treated with lovastatin for 24h before everolimus was added, and the combination of both drugs was incubated... by Svenja Nölting (566453)

DataSheet2_Combined Systemic Intake of K-ATP Opener (Nicorandil) and Mesenchymal Stem Cells Preconditioned With Nicorandil Alleviates Pancreatic Insufficiency in a Model of Bilater... by Asmaa Mohammed ShamsEldeen (11753462)

“…The pancreatic tissues showed a reduction in cellularity and a significant decrease in the expression of the cell survival pathway, PI3K/Akt/mTOR, in the I/R group compared to the control. …”

DataSheet1_Combined Systemic Intake of K-ATP Opener (Nicorandil) and Mesenchymal Stem Cells Preconditioned With Nicorandil Alleviates Pancreatic Insufficiency in a Model of Bilater... by Asmaa Mohammed ShamsEldeen (11753462)

“…The pancreatic tissues showed a reduction in cellularity and a significant decrease in the expression of the cell survival pathway, PI3K/Akt/mTOR, in the I/R group compared to the control. …”

Data_Sheet_1_Effectiveness of a Novel Nutraceutical Compound Containing Red Yeast Rice, Polymethoxyflavones and Antioxidants in the Modulation of Cholesterol Levels in Subjects Wit... by Paolo Cimaglia (4386445)

“…</p><p>Results: Fifty subjects completed the study. The treatment caused a significant decrease in LDL (−15.6%, p < 0.001), oxLDL (−21.5%, p < 0.001), total cholesterol (TC), triglycerides, and ApoB. …”

Geographic visualization of the predicted changes in the scale-adjusted metrics <i>D</i>_{<i>Y</i>_<i>i</i>}(<i>t</i>) between the years <i>t</i> = 2010 and <i>t<... by Luiz G. A. Alves (441209)

Data_Sheet_1_Dexmedetomidine only regimen for long-term sedation is associated with reduced vasopressor requirements in septic shock patients: A retrospective cohort study from MIM... by Lulan Li (10294175)

“…The primary outcome was the ratio of norepinephrine equivalent dose to mean arterial pressure (NEq/MAP) in the first 72 h after DEX or other sedatives for sedation. …”

Image_1_The fecal carriage rate of extended-spectrum β-lactamase–producing or carbapenem-resistant Enterobacterales among Japanese infants in the community at the 4-month health ex... by Soichiro Kawata (16329168)

“…Enterobacterales producing CTX-M-9 ± TEM were broadly distributed among the positive samples (65.5%), whereas the CTX-M-1 group was exclusively detected among those from “Hospital A”. …”

Data_Sheet_1_Impact of Prolonged COVID-19 Lockdown on Body Mass Index, Eating Habits, and Physical Activity of University Students in Bangladesh: A Web-Based Cross-Sectional Study.... by Md. Jamal Hossain (8697996)

“…The multinomial logistic regression analysis found a significant impact of gender [male vs. female: adjusted relative risk ratio (RRR) = 1.448; 95% confidence interval (CI) = 1.022, 2.053; p = 0.037], age (years) (<22 vs. >25: RRR =0.389, 95% CI = 0.213,0.710; p = 0.002, and 22–25 vs. >25: RRR = 0.473, 95% CI = 0.290, 0.772; p = 0.003), monthly family income (BDT) (<25,000 vs. >50,000: RRR = 0.525, 95% CI = 0.334,0.826; p = 0.005), university type (public vs. private: RRR = 0.540, 95% CI = 0.369, 0.791; p = 0.002), eating larger meals/snacks (increased vs. unchanged: RRR = 2.401, 95% CI = 1.597, 3.610; p < 0.001 and decreased vs. unchanged: RRR = 1.893, 95% CI = 1.218, 2.942; p = 0.005), and verbally or physically abuse (yes vs. no: RRR = 1.438, 95% CI = 0.977, 2.116; p = 0.066) on obesity during COVID-19 pandemic. …”

NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity by Omar A. Z. Tutakhel (3944741)

“…Our results show that in kidney transplant recipients treated with cyclosporine (n = 9) or tacrolimus (n = 23), the abundance of both tNCC and pNCC in uEVs is 4–5 fold higher than in CNI-free kidney transplant recipients (n = 13) or healthy volunteers (n = 6). …”

Risk of upper gastrointestinal bleeding with low-dose aspirin: case–control studies and cohort studies. by Luis A. García Rodríguez (594336)

“…^aData for duodenal bleeding and gastric bleeding (defined as bleeds located in the upper gastrointestinal tract, at sites other than the duodenum) [≤ 250 and 251–325 mg per day]; ^bData for plain, enteric-coated, and buffered aspirin; ^cData for different alcohol consumption categories (current drinker/never drinker/ex-drinker); ^dData for gastric ulcer and duodenal ulcer bleeding (defined as the presence of melena, haematemesis or haematochezia with a substantial decrease in haemoglobin and a peptic ulcer identified endoscopically); ^eData for primary and secondary prevention; ^fRisk of erosive esophagitis; ^gAcute defined as regular or sporadic aspirin use for 5–30 days before endoscopy; ^hChronic defined as regular aspirin use for more than 1 month before endoscopy; ⁱOR; ^jRR; ^kSIR; ^lHR. …”

Table_1_Reduced Preoperative Glomerular Filtration Rate Is Associated With Adverse Postoperative Oncological Prognosis in Patients Undergoing Radical Nephroureterectomy for Upper T... by Shijie Li (759509)

“…Multivariate regression analysis based on Cox proportional risk models and Kaplan-Meier survival rates showed that lower preoperative eGFR was associated with decreased OS, PFS, and CSS. In the adjusted Cox regression model, patients with normal and moderately reduced eGFRs had a decreased hazard for mortality, with adjusted hazard ratios of 0.13 [95% confidence interval (CI): 0.07–0.26] and 0.36 (95% CI: 0.18–0.73), respectively (P < 0.001). …”

Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca²⁺]i overload and NF-κB activation by Nadia A. Rivero-Segura (4006709)

Data_Sheet_1_Effect of viscous soluble dietary fiber on glucose and lipid metabolism in patients with type 2 diabetes mellitus: a systematic review and meta-analysis on randomized... by Kun Lu (404977)

“…</p>Results<p>Statistical significance was observed in the decreases of glycosylated hemoglobin (HbA1c) (mean difference) [MD = −0.47; 95%CI: (−0.66, −0.27)], fasting blood glucose (FBG) [MD = −0.93; 95%CI: (−1.46, −0.41)], total cholesterol (TC) [MD = −0.33; 95%CI: (−0.46, −0.21)], and low-density lipoprotein and cholesterol (LDL-C) [MD = −0.24; 95%CI: (−0.35, −0.13)]. …”

Statistical index <i>η</i> as a function of <i>I</i>_<i>CaL</i> for different values of <i>I</i>_<i>Kr</i>. by Enid Van Nieuwenhuyse (4669237)

“…<p>The calculation of <i>η</i> for a threshold of -60 mV and the last second of the burst pacing simulation. …”

DataSheet1_Effects of modified Danggui Sini Decoction as adjuvant therapy for angina pectoris in coronary heart disease: a systematic review and meta-analysis based on randomised c... by He Wang (250350)

“…The quality of included studies was assessed using the Cochrane Handbook version 5.1, and meta-analysis was executed via RevMan 5.4 software.…”

Fig 6 - by Anant Shinde (3954662)

Parallel trend test. by Wei Wang (17594)

Data_Sheet_1_The Marine Endophytic Polyamine-Producing Streptomyces mutabilis UAE1 Isolated From Extreme Niches in the Arabian Gulf Promotes the Performance of Mangrove (Avicennia... by Khaled A. El-Tarabily (5173520)

“…This was evident from the significant (P < 0.05) increases in dry weight and length of root (66.7 and 65.5%, respectively) and shoot (64.8 and 58.0%, respectively), number of branches (64.3%), total leaf area (40.2%), and photosynthetic pigments (54.5% chlorophyll a; 40.0% chlorophyll b; and 53.1% carotenoids) of mangrove compared to the PA-non-producing Streptomyces sp. or control treatment. …”

Genotypic Analyses of Shiga Toxin-Producing <em>Escherichia coli</em> O157 and Non-O157 Recovered from Feces of Domestic Animals on Rural Farms in Mexico by Bianca A. Amézquita-López (112648)

“…Most non-O157 isolates were <em>ehxA</em>-positive (86.5%, 32/37) but only 10.8% (4/37) harbored <em>eae</em>. …”

Schoenfeld residual tests. by Adane Petros (11320648)

“…</p><p>Conclusion</p><p>Our study found that peripheral venous catheter use for vasopressor administration in circulatory shock was associated with a low extravasation rate (1.2%), with all events occurring after more than five days, indicating it might be a safe alternative to CVC for short-term use in resource-limited settings. …”