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65281
c-Myc Represses Tumor-Suppressive microRNAs, let-7a, miR-16 and miR-29b, and Induces Cyclin D2-Mediated Cell Proliferation in Ewing’s Sarcoma Cell Line
Published 2015“…We also demonstrated that c-Myc-siRNA treatment of ES cells was associated with the decreased expression of CCND2 as a down-stream of three miRNAs. …”
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65282
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65283
Datasheet1_Impact of hypertensive heart disease, risk factors, and age-period-cohort models across 204 nations and regions from 1990 to 2019: a global perspective from the 2019 glo...
Published 2024“…The APC model revealed an association between mortality rates and age, with a decreasing mortality risk over time and improved survival rates for a later birth cohort.…”
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65284
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65285
Image_2_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe...
Published 2024“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. To test this hypothesis, GLP-1R<sup>+/+</sup> mice and GLP-1R null (GLP-1R<sup>-/-</sup>) mice were fed a high fat diet for 4 months to elicit diet-induced obesity prior to undergoing a sequential 3-day vehicle period, 3-day drug treatment (5, 10, 20 or 50 nmol/kg; GEP44 vs the selective GLP-1R agonist, exendin-4) and a 3-day washout. …”
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65286
Image_1_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe...
Published 2024“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. To test this hypothesis, GLP-1R<sup>+/+</sup> mice and GLP-1R null (GLP-1R<sup>-/-</sup>) mice were fed a high fat diet for 4 months to elicit diet-induced obesity prior to undergoing a sequential 3-day vehicle period, 3-day drug treatment (5, 10, 20 or 50 nmol/kg; GEP44 vs the selective GLP-1R agonist, exendin-4) and a 3-day washout. …”
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65287
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65288
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65289
Basal levels of (A) C/EBP-α, (B) GLUT4, (C) S100B, (D) PPAR-α, (E) PPAR-β/δ, (F) PPAR-γ, (G) TSPO, (H) PKCε mRNAs normalized to RPS18.
Published 2013“…<p>Cells were seeded and collected after the indicated time points; day 0 represents one day after the plating. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028750#s3" target="_blank">Results</a> are expressed in terms of mean and S.E.M., calculated from 3 independent experiments and presented as fold increase or decrease from the value measured on day 0. …”
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65290
(A) Location of the study site, sea ice extent and GPS tracks from (B) 2012 and (C) 2014 and (D) 75% kernel contours of resting and foraging positions in 2012 (green), and 2014 (pi...
Published 2016“…<p>1A: General map situating Ukaleqarteq (red dot) and the location of the studied area (red rectangle) represented in Figs 1B, 1C, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157764#pone.0157764.g005" target="_blank">5A</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157764#pone.0157764.s001" target="_blank">S1</a>. 1B and 1C: GPS tracks: red dots correspond to foraging or resting (speed <10 km.h<sup>-1</sup>) and black dots to travelling (speed >10 km.h<sup>-1</sup>). …”
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65291
Data: Median heart rate per minute of motionless dolphins at surface from Towards non-invasive heart rate monitoring in free-ranging cetaceans: a unipolar suction cup tag measured...
Published 2021“…We observed large heart rate oscillations corresponding to respiration in the motionless whales during surfacing (a false killer whale, mean 47 bpm, range 20–75 bpm; Risso's dolphins, mean ± s.d., 61 ± 15 bpm, range 28–120 bpm, <i>n</i> = 4 individuals), which was consistent with the sinus arrhythmia pattern (eupneic tachycardia and apneic bradycardia) observed in other cetaceans. …”
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65292
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65293
Synthesis, Crystal Structure and Magnetic Characterization of a Series of Cu<sup>II</sup>–Ln<sup>III</sup> Heterometallic [Ln = La, Ce, Pr, Nd and Sm) Metal–Organic Compounds with...
Published 2013“…This phase transition is accompanied by a compression of the crystallographic <i>b</i>-axis in the range 2.4 to 2.8 Å with the consequent decrease of the unit cell volume from 9.5% to 12%. …”
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65294
Synthesis, Crystal Structure and Magnetic Characterization of a Series of Cu<sup>II</sup>–Ln<sup>III</sup> Heterometallic [Ln = La, Ce, Pr, Nd and Sm) Metal–Organic Compounds with...
Published 2013“…This phase transition is accompanied by a compression of the crystallographic <i>b</i>-axis in the range 2.4 to 2.8 Å with the consequent decrease of the unit cell volume from 9.5% to 12%. …”
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65295
Comparison of preoperative remission scores and diabetes duration alone as predictors of durable type 2 diabetes remission and risk of diabetes complications after bariatric surger...
Published 2020“…Partial remission (after 2 and 10 years) was defined as blood glucose <6.1 mmol/L or HbA1c <6.5% (48 mmol/mol) and no diabetes medication. …”
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65296
Supplementary file 1_Comparative effects of high-intensity interval training versus moderate-intensity continuous training on body composition and blood pressure in overweight adol...
Published 2025“…The methodological rigor of the selected studies was evaluated through a revised evaluation approach based on PRISMA guidelines. …”
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65297
DataSheet_2_Efficacy and Safety of Bone Marrow-Derived Mesenchymal Stem Cells for Chronic Antibody-Mediated Rejection After Kidney Transplantation- A Single-Arm, Two-Dosing-Regimen...
Published 2021“…Flow cytometry analysis showed a significant decreasing trend of CD27<sup>-</sup>IgD<sup>-</sup> double negative B cells subsets and trend towards the increase of CD3<sup>+</sup>CD4<sup>+</sup>PD-1<sup>+</sup>/lymphocyte population after MSCs therapy. …”
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65298
DataSheet_1_Efficacy and Safety of Bone Marrow-Derived Mesenchymal Stem Cells for Chronic Antibody-Mediated Rejection After Kidney Transplantation- A Single-Arm, Two-Dosing-Regimen...
Published 2021“…Flow cytometry analysis showed a significant decreasing trend of CD27<sup>-</sup>IgD<sup>-</sup> double negative B cells subsets and trend towards the increase of CD3<sup>+</sup>CD4<sup>+</sup>PD-1<sup>+</sup>/lymphocyte population after MSCs therapy. …”
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65299
FIGURE 7 from Antibody–Drug Conjugate αEGFR-E-P125A Reduces Triple-negative Breast Cancer Vasculogenic Mimicry, Motility, and Metastasis through Inhibition of EGFR, Integrin, and F...
Published 2024“…<b>D,</b> Tumor sizes of five representative tumors from each treatment group (<i>n</i> = 5 for PBS due to death of 2 mice, and <i>n</i> = 7 for E-P125A, cetuximab, and αEGFR-E-P125A groups). …”
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65300
Table_1_HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure.xlsx
Published 2021“…<p>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19) was announced as an outbreak by the World Health Organization (WHO) in January 2020 and as a pandemic in March 2020. …”