S270 phosphorylation is different at different synapses. by Heba Kalbouneh (610559)

“…The scale bar represents 10 µm. (A′, B′, E) Upon treatment with CDK5 inhibitor SU9516 (5 µM) for six hours the phosphorylation of gephyrin is significantly reduced. …”

Down-regulation of PCNA increases the number of oocytes by alleviating the apoptosis of oocytes in fetal mouse ovaries. by Bo Xu (233514)

“…(<b>F</b>) mRNA expression of apoptosis-related genes was quantified by real-time PCR in PCNA RNAi and control ovaries 96 hours after transfection. Each bar represents a mean±s.d. of 20 (B), 12 (D) and 16 (E) ovaries from three or five independent experiments in different animals. #: P<0.05, ##: P<0.01, unpaired t test, *: P<0.05, **: P<0.01, student's t-test, compared with concurrent controls.…”

Enrichment and stability of synaptoneurosomes. by Celia Williams (265997)

“…Densitometric comparison on immunoblots of postsynaptic proteins PSD-95, NMDAR1 and GluR2 in synaptoneurosomes shows more than a two-fold enrichment compared to homogenates, an increase in presynaptic protein SNAP-25 but a 40% decrease in glial protein GFAP. …”

Development of tLyP-1 functionalized nanoliposomes with tunable internal water phase for glioma targeting by Yajing Wang (447120)

Binding and uptake of B3501 and B-4131 with human brain endothelial cell line, hCMEC/D3. by Wilber Sabiiti (170648)

“…Like the H99-cap59 pair, live CFU counts showed a time dependent decrease in the number of associated cryptococci by 4 hr of incubation, ★ = P<0.01, ★★ = P<0.01 for both B3501 and B4131. …”

The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice by Tatsuya Shimomatsu (1545943)

“…The average number of mast cells was 81, 50, and 12 (magnification, ×100), the mortality rate was 24%, 8%, and 9% and the mean body weight gain was 4.6 g, 8.0 g and 5.1 g, respectively.…”

Effects of p-ERK1/2 and p-p38MAPK inhibitors on TNFα-induced occludin expression in hCMEC/D3 cells. by Yawen Ni (3723304)

“…Quantification of protein band intensity was determined through PItotal/PIβ-actin and then normalized to control. Results are mean ± SD from 5 or more experiments. Two-way ANOVA revealed a significant main effect of TNFα (p<0.0001) and the inhibitors (p = 0.0287). …”

CoCl₂ induces abnormal neovascularization in zebrafish embryos. by Yu-Ching Wu (739844)

“…(B) With fluorescence excitation, ectopic SIV and excessive retinal vascularization are shown in CoCl_<b>2</b>-treated embryos compared with the untreated control. (C, D) A dose-dependent decrease in survival rates (four independent experiments; n = 35 in each group) in embryos treated with increasing concentrations (0–20 mM) and an increase in the vascular defect occurrence rate in the SIV and retinal vessels are shown (three independent experiments; n = 35 in each group). …”

Characteristics of the studied population. by Ana Paula Thiesen (14846189)

“…The sample size was calculated for a minimum of 7 cases and 7 controls, having a power = 90%, an α error = 5%, and a standard deviation of 20, to identify a decrease from the average of 40 DAB units (control) to 4 DAB units in cancer. …”

S1 File - by Ana Paula Thiesen (14846189)

“…The sample size was calculated for a minimum of 7 cases and 7 controls, having a power = 90%, an α error = 5%, and a standard deviation of 20, to identify a decrease from the average of 40 DAB units (control) to 4 DAB units in cancer. …”

HDAC inhibition induces global changes in alternative splicing. by Jarmila Hnilicová (231016)

“…(B) Exons with high change (≥3-fold) were analyzed with respect to their inclusion or exclusion and divided into three groups according to the expression of a gene where the alternative exons are localized. …”

Optical coherence tomography angiography findings in patients with branch retinal vein occlusion treated with Anti-VEGF by Emine Ciloglu (8047937)

“…The mean central macular thickness was significantly higher in eyes with branch retinal vein occlusion than in controls, and we observed a significant decrease in central macular thickness after anti-VEGF treatment (<0.001). …”

Optical coherence tomography angiography findings in patients with branch retinal vein occlusion treated with Anti-VEGF by Emine Ciloglu (8047937)

“…The mean central macular thickness was significantly higher in eyes with branch retinal vein occlusion than in controls, and we observed a significant decrease in central macular thickness after anti-VEGF treatment (<0.001). …”

Variation of up- and down-regulated transcripts with time post-infection. by Carolina Ramírez (124070)

“…The decreasing response of the up-regulated gene transcripts with time is evident; the number of down-regulated genes is relatively consistent across the time points. …”

Increased Oxidative Damage in Carriers of the Germline <em>TP53</em> p.R337H Mutation by Gabriel S. Macedo (128234)

“…Mutation carriers also showed a four-fold increase in plasma malondialdehyde levels, indicating increased lipid peroxidation (NC = 40.20±0.71, C = 160.5±0.88, <em>P</em><0.0001). …”

MSL-distance associated with distinct germline regulation and ancestral expression patterns. by Kevin H-C. Wei (7879079)

“…The fold changes in X:A ratio between testes cell stages are depicted in log scale for the different gene categories, with greater and less than 0 values representing increase and decrease in expression. …”

Image_1_NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway.pdf by Shanyu Fang (11058009)

“…Here, clinical data showed that the level of netrin-G1 (NTNG1) in cisplatin-resistant cancer was higher than that in cisplatin-sensitive cancer (2.2-fold, p = 0.005); patients with a high NTNG1 level in cancer tissues had shorter progression-free survival (11.0 vs. 25.0 months, p = 0.010) and platinum-free interval (5.0 vs. 20.0 months, p = 0.021) compared with patients with a low level. …”

Salinity induces unique changes in lipid classes and fatty acids of the estuarine haptophyte <i>Diacronema vlkianum</i> by José-Pedro Cañavate (11771443)

“…Hypersalinity caused a slight, although significant, sulpholipid decrease and a 4-fold increase in phosphatidylglycerol, suggesting a key role for this phospholipid in salt tolerance. …”

Effect of <i>edin</i> RNAi on <i>Drosophila</i> immune signaling in vitro. by Leena-Maija Vanha-aho (323292)

“…The Imd pathway was activated by adding heat-killed <i>E. coli</i> to the cell culture medium and samples were collected at indicated time points. <i>Edin</i> RNAi causes a 30% decrease in the Imd pathway activity at the 24 h time point. …”

Arf4 overexpression rescues spine loss in apoE4-expressing primary neurons. by Sachi Jain (108277)

“…<p>(<i>A</i>) Representative Western blot of actin and Arf4 levels in NSE-apoE4 and -apoE3 mice reveal a decrease in Arf4 protein levels from NSE-apoE4 mice compared to those from NSE-apoE3 mice. …”