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Image5_Decreasing incidence and mortality of lung cancer in Hungary between 2011 and 2021 revealed by robust estimates reconciling multiple data sources.TIFF
Published 2024“…The COVID-19 pandemic resulted in a statistically significant decrease in lung cancer incidence, especially in the 50–59 age group (both sexes).…”
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8069
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Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A
Published 2010“…Mutations in NS5A alone conferred decreased CsA susceptibility regardless of NS5B mutations.…”
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8074
Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs
Published 2022“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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8075
Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs
Published 2022“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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8076
Proposed model of miR-199a-5p profibrotic function in lung fibrogenesis.
Published 2013“…Production of miR-199a-5p in response to TGFβ in lung fibroblasts results in CAV1 downregulation and subsequently, impaired TGFβ/TGFβR complex degradation. …”
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8077
Mean values of predictors per stratum per treatment.
Published 2015“…</p><p>Definition of abbreviations: postbr. = postbronchodilator; FEV<sub>1</sub> = forced expiratory volume in one second; % pred = percentage of predicted value; PC<sub>20</sub> methacholine = the provocative concentration of methacholine that causes a decrease in FEV<sub>1</sub> of 20%; RV/TLC = residual volume/total lung capacity; TLCO = diffusion capacity of the lung for carbon monoxide.…”
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