ITC analysis of ligand binding. by Jenni Leppiniemi (166920)

“…<p>Thermograms of measurements performed at three different temperatures (<b>A</b>) 15°C, (<b>B</b>) 25°C and (<b>C</b>) 40°C are shown. …”

EGFP expression driven by the <i>Isl2b</i> promoter facilitates observation of dorsal root ganglia development concurrent with degeneration of Rohon-Beard (R-B) neurons. by Yu-Jin Won (312845)

“…The contrast of the images was adjusted to emphasize EGFP-labeled sensory neurons. Scale bar in A represents 0.5 mm and the other scale bars represent 50 µm.…”

Expression of thrombin receptors, α_IIbβ₃ and P-selectin in PP1cγ^−/− platelets. by Francisca C. Gushiken (368549)

“…Results are expressed as ±SEM of 5–6 experiments. Compared to thrombin stimulated WT platelets, the decreased binding of JON/A antibody to PP1cγ^−/− platelets was significant at *p = 0.003.…”

Expression analysis of pancreatic endocrine hormones. by Alan W. Hart (289465)

“…<p>Images show immuno-stainings for insulin (<b>A</b>, <b>B</b>), glucagon (<b>C</b>, <b>D</b>), and somatostatin (<b>E, F</b>) in sections through the pancreas of control (<b>A</b>, <b>C</b>, <b>E</b>) and CPTD6 (<b>B</b>, <b>D</b>, <b>F</b>) mice sacrificed 5 weeks post-injections. …”

Plk1 is important for cleavage of the Scc1 sensor. by Fikret Gurkan Agircan (641709)

“…<p>(A) HeLa cells were incubated with 5 µM STLC and with or without 100 nM BI2536 for 1 h. …”

Distribution of haptoglobin genotypes in the presence or absence of PCOS, obesity, or disordered glucose tolerance. by Francisco Álvarez-Blasco (372908)

“…<p>There was a borderline significant tendency towards an increased frequency of <i>Hp²/Hp²</i> genotype, and a decreased frequency of the <i>Hp¹/Hp¹</i> genotype, in PCOS patients compared with non-hyperandrogenic controls (χ² = 5.220, <i>P</i> = 0.074 overall; χ² = 3.650, <i>P</i> = 0.056 for a dominant model; χ² = 3.521, <i>P</i> = 0.061 for a recessive model).…”

Effects of Dissociation Rate on Calcium Enhancement of Dopamine-Induced PKAc Elevation and PP1 Suppression by Maria Lindskog (65533)

“…All panels show the effect of dissociation rate on the response to dopamine alone (green dashed line, stars), calcium alone (blue dashed line, circles), and paired dopamine and calcium (red dashed line, squares).</p><p>(A) Response is independent of rate of calcium-dependent AC5 inhibition.…”

Suppression of periosteal hypertrophy by inhibition of remodeling of actin cytoskeleton by ROCK inhibitor. by Daisuke Sakai (174973)

“…In the loaded and ROCK inhibitor-injected left tibia, the periosteal thickness was decreased in a dose-dependent manner (25 mg/kg, 50 mg/kg, 75 mg/kg). …”

Reaction norms that evolved at different adhesion costs. by Jordi van Gestel (110582)

“…Each reaction norm shows the probability of adhesion (<i>P</i>) as a function of both the fraction of adhesive cells and the fraction of kin in a cell’s neighborhood (i.e., the 6 neighboring positions surrounding a cell on the hexagonal surface). …”

Up-regulation of Y515 is necessary for Sig-1R-mediated neurite outgrowth. by Yuriko Kimura (468307)

“…Without BDNF, PRE-084 alone did not increase TrkB phosphorylation. ND: not determined, (A) n = 5, (B) n = 3, **<i>P</i><0.01, Scheffe’s test. …”

Refitting process schematic by C T Chantler (557430)

“…The peak energy of the titanium Kβ spectral profile is found to be 4931.966 ± 0.022 eV prior to instrumental broadening. This 4.5 ppm result decreases the uncertainty over the past literature by a factor of 2.6 and is 2.4 standard deviations from the previous standard. …”

Derived from inclusions late in the infectious cycle induce aponecrosis in human aortic endothelial cells-1 by Joseph Marino (85091)

“…F: HAEC infected for 72 h with 5 IFU/cell. Note that although the cells are infected with different infection doses and fixed at different time points they both elicit the same cell death morphology, thus excluding a cytotoxic effect and underlining the independency of cell death morphology from infection time. …”

Table 1_Effects of two different variants in the MAGT1 gene on B cell subsets, platelet function, and cell glycome composition.pdf by Lucía del Pino Molina (15407477)

“…</p>Methods<p>We performed a functional validation of these two variants in the MAGT1 gene and their association with decreased NKG2D expression, uncontrolled EBV viremia, and the development of lymphoma-associated complications in three members of the same family.…”

DataSheet_1_Fecal and serum metabolomic signatures and gut microbiota characteristics of allergic rhinitis mice model.docx by Zhen Chen (129176)

“…Interestingly, one of the significant difference metabolites, α-Linoleic acid (ALA), decreased consistently in feces and serum of AR. KEGG functional enrichment analysis and correlation analysis showed a close relationship between differential serum metabolites and fecal metabolites, and changes in fecal and serum metabolic patterns are associated with altered gut microbiota in AR. …”

Nanog interferes with the binding of β-catenin to Tcf7 in vitro and in vivo. by Mudan He (7017239)

“…Co-transfection of increasing amount of Nanog decreases the interaction between β-catenin and Tcf7 in a dose-dependent manner. …”

Table 1_Association of magnesium depletion score with serum anti-aging protein Klotho in the middle-aged and older populations.docx by Zhijie Zhuang (17669958)

“…Participants were divided into three groups based on MDS: low (0–1 points), middle (2 points), and high (3–5 points), reflecting cumulative risks of magnesium depletion derived from diuretic use, proton pump inhibitors, renal function, and alcohol intake. …”

Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease by Marco Medici (280307)

“…Individual and combined effects (genetic risk scores) of these variants on (subclinical) hypo- and hyperthyroidism, goiter and thyroid cancer were studied. Individuals with a high genetic risk score had, besides an increased risk of TPOAb-positivity (OR: 2.18, 95% CI 1.68–2.81, <i>P</i> = 8.1×10⁻⁸), a higher risk of increased thyroid-stimulating hormone levels (OR: 1.51, 95% CI 1.26–1.82, <i>P</i> = 2.9×10⁻⁶), as well as a decreased risk of goiter (OR: 0.77, 95% CI 0.66–0.89, <i>P</i> = 6.5×10⁻⁴). …”

Enantioselective Photochemical Reactions of 2-Pyridones in Solution by Thorsten Bach (1397326)

“…Two key photochemical reactions of prochiral 2-pyridones were studied in the presence of a chiral host. The [4 + 4]-photocycloaddition with cyclopentadiene (CpH) proceeded smoothly and with high enantioselectivity (84−87% ee). …”

Increased paternal age at birth is negatively associated with overall variance in gene expression in peripheral blood lymphocytes (PBL) of normal children. by Mark D. Alter (139909)

“…We found that the association of autism with decreased overall variance was only found in children of younger fathers and represented a difference of .78 standard deviations within our sample (p = .0007) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0016715#pone-0016715-g003" target="_blank">figure 3b</a>). …”

SEAwise Report on the impacts of fisheries on stocks and landings under SEAwise EBFM by Dorleta Garcia (12315201)

“…<i>Trawl Ban scenarios</i> where the effort of bottom trawlers was reduced by a 50% and different options were analysed for the static gears</p><p dir="ltr">5. …”