Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

Decreased Klotho expression in kidneys from hyperlipidemic mice. by Cristina Sastre (503532)

Decreased energy intake in Het GIP Tg mice. by Su-Jin Kim (90561)

Bone mass and formation are decreased in Akt1-/- mice. by Naohiro Kawamura (33999)

Decreased fibrin deposition in hypoxic C3−/− mice. by Eileen M. Bauer (337320)

Decreased NTAL expression after shRNA silencing. by Iva Polakovicova (621362)

FLZ decreased the expression of phospho-APP and APP-CTF. by Xiu-Qi Bao (479278)

TGF-β1 decreases RECK expression in fibroblasts. by Jaime Gutiérrez (401710)

RNF5 loss decreases PEL xenograft tumor growth and cell cycle gene expression. by Xiaojuan Li (351842)

Lack of TLR signaling (MyD88^-/-) results in decreased levels of cytokines in the cornea. by Rose Y. Reins (2586106)

Blocking C5L2 decreased C5a-primed neutrophils for ANCA-induced respiratory burst. by Jian Hao (160736)

SPL treatment decreases diabetes-induced co-immunoprecipitation (co-IP) of cldn-4 and -8. by Eduardo Molina-Jijón (4020464)

“…Also, increased co-IP of cldn-8 with cldn-4 was found under diabetic condition and SPL decreased this interaction (C), densitometric analysis show that these changes were significant (D) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0177362#pone.0177362.s005" target="_blank">S5 Fig</a>). …”

Loss of <i>SLC4A11</i> expression and CHED-associated <i>SLC4A11</i> mutations in hCEnC lead to decreased cell viability during tBH-induced oxidative stress. by Doug D. Chung (3611387)

SPL treatment decreases diabetes-induced decrement in protein expression of cldn-5 in glomeruli (GL) and cldn-2 and occldn in proximal tubules (PT). by Eduardo Molina-Jijón (4020464)

“…<p>SPL prevents diabetes-induced decrease of cldn-5 protein expression (A and B) in GL, and mRNA (F) and protein expression of cldn-2 (A and C), and protein expression of occldn (A and D) in PT (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0177362#pone.0177362.s002" target="_blank">S2 Fig</a>). …”

Activation, inactivation, and deactivation kinetics differ between Ca_V3.3 WT and variants as well as among the variants. by Yousra El Ghaleb (22075892)

Subjects:

Promoter reporter studies for SF-1 regulating the human <i>BDNF</i> promoter I and comparative studies of specific <i>NR5A1</i> mutations on <i>BDNF</i> promoter activity. by Jana Malikova (615672)

Subjects:

Promoter reporter studies for reported <i>NR5A1</i> mutations by Jana Malikova (615672)

Subjects:

A homozygous point mutation in the <i>Mrps34</i> gene causes a decrease in the MRPS34 protein. by Tara R. Richman (713532)

“…The 5′- and 3′-untranslated regions are shown as grey boxes and the predicted mitochondrial targeting sequence is shown as a black box (predicted using MitoProtII, [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005089#pgen.1005089.ref040" target="_blank">40</a>]). …”

<i>Dmd^mdx</i> rats are characterized by muscle weakness and by a decrease in a spontaneous activity. by Thibaut Larcher (331981)

“…<i>Dmd^mdx</i> rats showed fatigue with a decreased force grip across the five pulls, and significant values are obtained for the two last trials that were reduced to ∼70% when compared to Trial 1. …”

Reduced callose synthesis in <i>pat</i> is associated with the decreased <i>CalS5</i> expression. by Shuang-Xi Xiong (8844044)