Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol expo... by Frederik Abel (8452101)

“…Hypoxia increased apoptosis of H9c2 cells (hypoxia: 8.4%±0.6; normoxia: 2.5%±0.1; p<0.0001). RIPC-EVs decreased H9c2 cell apoptosis compared to control (apoptotic ratio: 0.83; p = 0.0429) while Sham-EVs showed no protection (apoptotic ratio: 0.97). …”

Synthesis of Binucleating Macrocycles and Their Nickel(II) Hydroxo- and Cyano-Bridged Complexes with Divalent Ions: Anatomical Variation of Ligand Features by Xiaofeng Zhang (172446)

“…Syntheses of macrocycle <b>5</b> with a 7-Me-[12]­aneSN₃ and macrocycle <b>6</b> with a 1,8-Me₂-[14]­aneN₄ M^II binding site are described together with hydoxo-bridged Ni/Cu and cyano-bridged Ni/Fe complexes. …”

Lowering intracellular c-di-GMP reduces Vc1-dependent gene expression. by Ankunda T. Kariisa (2155555)

“…Increasing PDE production corresponds with decreasing intracellular c-di-GMP. (A and B) Measurements of β-galactosidase activity were done with at least three independent biological samples, and the means and standard error are shown. * <i>P</i> < 0.05, *** <i>P</i> < 0.001, n.s. = not significant by one-way ANOVA and Bonferroni’s multiple comparison test.…”

Depletion of endogenous ME2 enhances ROS generation, increases NAD⁺/NADH and NADP/NADPH ratios and decreases ATP levels. by Jian-Guo Ren (242581)

Salinity Tolerance and Osmoadaptation Strategies in Four Genera of Anammox Bacteria: <i>Brocadia</i>, <i>Jettenia</i>, <i>Kuenenia</i>, and <i>Scalindua</i> by Satoshi Okabe (1740976)

“…Scalindua sp.” showed optimum growth at 1.5–3% salinity and was tolerant to ∼10% salinity (a slight halophile). …”

Human Embryonic Stem Cell-Derived Mesenchymal Stromal Cells Decrease the Development of Severe Experimental Autoimmune Uveitis in B10.RIII Mice by Yu Qin (166316)

“…<p><i>Purpose</i>: We investigated the effect of exogenously administered human embryonic stem cell-derived mesenchymal stromal cells (hESC-MSCs) in experimental autoimmune uveitis (EAU) in B10.RIII mice, a murine model of severe uveitis.</p> <p><i>Methods</i>: B10.RIII mice were immunized with an uveitogenic peptide, and intraperitoneal injections of 5 million hESC-MSCs per animal were given on the same day. …”

When policy meets the pedal: A reduction in motorcyclist fatalities following the implementation of a road traffic law in Lagos, Nigeria by Chinmayee Venkatraman (7541369)

“…The Welch’s ANOVA yielded a statistically significant difference between the Periods’ means (p < 0.0001). …”

Substrate specificity of YqfB and D8_RL amidohydrolases. by Viktorija Preitakaitė (17508980)

IL-6-induction of Nox2 and subsequent decrease of parvalbumin and GAD67 expression in PV-positive interneurons is NFκB-dependent. by Laura L. Dugan (264427)

“…<p>Nuclear extracts of brain samples obtained from wild-type or IL-6-deficient animals were analyzed for content of the NFkB p65 subunit by colorimetric quantification of p65 using a commercially available kit (TransAM). A high concentration of p65 was found in nuclear extracts obtained from old wild type mice (a), and this was greatly diminished in nuclear extracts obtained from similar-age IL-6 deficient mice. …”

MTT assay of the HCT116 cell lines expressing YqfB or D8_RL after exposure to 10 μM of prodrugs. by Viktorija Preitakaitė (17508980)

Decreased TNAP enzyme activity and up-regulated expression of <i>Fgfr3</i> mRNA in <i>Hyp</i> osteocytes in vivo. by Sathish K. Murali (2585914)

CPGF NPs induce apoptosis in breast cancer cells. by Kirtee D. Wani (636463)

“…<p>(<b>A</b>) CPGF NPs decreased the mitochondrial membrane potential of the breast cancer cell lines as observed by JC-1 staining. …”

S1 Data - by Sinthia Kabir Mumu (17705902)

“…The result is substantiated by significant decrease in blood glucose level in prevention (29.5 mg/dL; <i>p</i> = 0.002) and treatment (31.5 mg/dL; <i>p</i> = 0.006) groups, compared to stress group (47.33 mg/dL) at the end of the experiment. …”

S2 Data - by Sinthia Kabir Mumu (17705902)

“…The result is substantiated by significant decrease in blood glucose level in prevention (29.5 mg/dL; <i>p</i> = 0.002) and treatment (31.5 mg/dL; <i>p</i> = 0.006) groups, compared to stress group (47.33 mg/dL) at the end of the experiment. …”

Mohr’s circles of soft rocks at different temperatures. by Zhenhua Wang (426041)

Phenotypic characterization of <i>E. faecalis</i> V583ΔABC<i>pp5-</i> in the absence or presence of 100 μM AI-2:(A) Biofim assay comparing attachment in the <i>pp5-</i> muntant in... by Friederike S. Rossmann (694730)

“…<p><b>(A)</b> Ability to form biofilms in microtiter plates in the presence of 100 μM AI-2 was measured in <i>pp5-</i> mutant and <i>E. faecalis</i> V583ΔABC. …”

Monocytes decrease the lysis of hMSCs by the NK cells, but significantly augment the secretion of IFN-γ in the co-cultures of NK, monocyte and hMSCs. by Han-Ching Tseng (245575)

EndoS treatment of rabbit anti-mCOL7 IgG decreases neutrophil activation by immobilized immune complexes <i>in vitro</i>. by Xinhua Yu (73299)

Point Application Therapy Targeting Feishu, Pishu and Shenshu Attenuates Asthma by Suppressing Autophagy and the AMPK-mTOR Signalling Pathway by Yutong Jin (2873837)

Data_Sheet_5_Synergistic Effect of MC-LR and C-Terminal Truncated HBx on HepG2 Cells and Their Effects on PP2A Mediated Downstream Target of MAPK Signaling Pathway.PDF by Chanchan Xiao (9522614)