Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

The correlation of the mitochondrial dynamics–related genes with Klf5 in mouse VSMCs. by Dong Ma (584680)

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Shark liver oil consumption decreases contractility in EDL muscle of trained rats by João Victor Capelli Peixoto (8301123)

“…In the supplemented group, animals were supplemented with SLO (1 g/kg) five times a week for eight weeks. Method: Contractile parameters as maximum isometric twitch force (Tmax), maximum speed of force development (+dF/dt), maximum speed of force decrease (-dF/dt), maximum tetanic force (Fmax) and resistance to fatigue were analyzed in isolated muscle. …”

Klf5 down-regulation leads to human VSMC senescence. by Dong Ma (584680)

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Klf5 deficiency in mouse VSMCs leads to mitochondrial fission. by Dong Ma (584680)

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Cardiac function assessed by echocardiography in Ang II–infused young (3 months) or old (18 months) WT and smcKlf5^−/− mice. by Dong Ma (584680)

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Representative TUNEL- and DAPI-stained sections from the abdominal aortas of young and old WT and smcKlf5^−/− mice following 28 days of Ang II infusion. by Dong Ma (584680)

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NAC suppresses Ang II–induced mitochondrial fission in mouse VSMCs. by Dong Ma (584680)

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Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

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AGE-modification of laminin leads to a decrease in Kir4.1 function. by Kayla Thompson (4885036)

GF mice have decreased levels of innate and adaptive immune effectors at the ocular surface. by Abirami Kugadas (3131940)

“…<p>A. Significantly decreased levels of complement proteins at the ocular surface in GF mice compared to SPF mice. …”

Decrease in the overall level of DNA in a cell after the injection into the cytoplasm or the nucleus by Noriaki Shimizu (12106)

A low dose of BTZ decreases proteasome activity with no effect on cell viability. by A. L. Furfaro (2587792)

Sildenafil decreases intestinal transit time in a DSS-recovery model of IBS. by Sarah K. Sharman (3966476)

ADAR2 was decreased in retina in a glaucoma model with chronic elevated IOP. by Ai Ling Wang (90011)

“…The mRNA levels of GluA2 and Rest were not changed (p>0.05, n = 5). (D). …”

Descriptives of the study sample, N = 451. by Orrin D. Ware (14829115)

A summary of calibration standards (n = 3). by Ewa Paszkowska (21246702)

“…<div><p>Purpose</p><p>Statins are the most commonly used drugs worldwide. Besides a significant decrease in cardiovascular diseases (CVDs) risk, the use of statins is also connected with a broad beneficial pleiotropic effect. …”

Nivalenol (NIV) decreases chondrocyte viability in a dose and duration-dependent manner. by Siyuan Li (178640)

CaA decreases the CSCs-like properties of malignant HaCaT cells. by Ye Yang (297214)

Decreased lethality in mice after intracranial injection with VSV-ΔP. by Phonphimon Wongthida (2836955)