Showing 8,721 - 8,740 results of 124,877 for search '(( a n decrease ) OR ( 5 ((((point decrease) OR (fold decrease))) OR (a decrease)) ))', query time: 1.73s Refine Results
  1. 8721
  2. 8722

    Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators by Shuai Wang (109515)

    Published 2020
    “…In this work, we reported the structure-based design of triazolo­[1,5-<i>a</i>]­pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC<sub>50</sub> = 22.02 nM). …”
  3. 8723

    Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators by Shuai Wang (109515)

    Published 2020
    “…In this work, we reported the structure-based design of triazolo­[1,5-<i>a</i>]­pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC<sub>50</sub> = 22.02 nM). …”
  4. 8724

    Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators by Shuai Wang (109515)

    Published 2020
    “…In this work, we reported the structure-based design of triazolo­[1,5-<i>a</i>]­pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC<sub>50</sub> = 22.02 nM). …”
  5. 8725

    Image_2_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla... by Chenhaoyi Xu (12456795)

    Published 2022
    “…However, it is unclear whether N6-methyladenosine (m<sup>6</sup>A) engages in the epigenetic modification of ARC. …”
  6. 8726

    Table_1_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla... by Chenhaoyi Xu (12456795)

    Published 2022
    “…However, it is unclear whether N6-methyladenosine (m<sup>6</sup>A) engages in the epigenetic modification of ARC. …”
  7. 8727

    Image_1_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla... by Chenhaoyi Xu (12456795)

    Published 2022
    “…However, it is unclear whether N6-methyladenosine (m<sup>6</sup>A) engages in the epigenetic modification of ARC. …”
  8. 8728

    Table_2_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla... by Chenhaoyi Xu (12456795)

    Published 2022
    “…However, it is unclear whether N6-methyladenosine (m<sup>6</sup>A) engages in the epigenetic modification of ARC. …”
  9. 8729
  10. 8730
  11. 8731
  12. 8732
  13. 8733
  14. 8734
  15. 8735

    THS exposure in conjunction with antioxidant treatment for 2.5 and 5 months alleviates metabolic syndrome in a dose-dependent manner. by Neema Adhami (516427)

    Published 2016
    “…<p><b>(A)</b> THS-exposed mice treated with antioxidants for 5 months have reduced visceral fat accumulation compared to THS exposed mice. …”
  16. 8736

    Self-Diffusive Properties of the Intrinsically Disordered Protein Histatin 5 and the Impact of Crowding Thereon: A Combined Neutron Spectroscopy and Molecular Dynamics Simulation S... by Eric Fagerberg (6662456)

    Published 2022
    “…Intrinsically disordered proteins (IDPs) are proteins that, in comparison with globular/structured proteins, lack a distinct tertiary structure. Here, we use the model IDP, Histatin 5, for studying its dynamical properties under self-crowding conditions with quasi-elastic neutron scattering in combination with full atomistic molecular dynamics (MD) simulations. …”
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