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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
n decrease » nn decrease (Expand Search), _ decrease (Expand Search), _ decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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8721
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8722
Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators
Published 2020“…In this work, we reported the structure-based design of triazolo[1,5-<i>a</i>]pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC<sub>50</sub> = 22.02 nM). …”
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8723
Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators
Published 2020“…In this work, we reported the structure-based design of triazolo[1,5-<i>a</i>]pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC<sub>50</sub> = 22.02 nM). …”
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8724
Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators
Published 2020“…In this work, we reported the structure-based design of triazolo[1,5-<i>a</i>]pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC<sub>50</sub> = 22.02 nM). …”
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8725
Image_2_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla...
Published 2022“…However, it is unclear whether N6-methyladenosine (m<sup>6</sup>A) engages in the epigenetic modification of ARC. …”
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8726
Table_1_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla...
Published 2022“…However, it is unclear whether N6-methyladenosine (m<sup>6</sup>A) engages in the epigenetic modification of ARC. …”
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8727
Image_1_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla...
Published 2022“…However, it is unclear whether N6-methyladenosine (m<sup>6</sup>A) engages in the epigenetic modification of ARC. …”
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8728
Table_2_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla...
Published 2022“…However, it is unclear whether N6-methyladenosine (m<sup>6</sup>A) engages in the epigenetic modification of ARC. …”
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8729
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8730
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8731
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8732
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8733
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8734
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8735
THS exposure in conjunction with antioxidant treatment for 2.5 and 5 months alleviates metabolic syndrome in a dose-dependent manner.
Published 2016“…<p><b>(A)</b> THS-exposed mice treated with antioxidants for 5 months have reduced visceral fat accumulation compared to THS exposed mice. …”
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8736
Self-Diffusive Properties of the Intrinsically Disordered Protein Histatin 5 and the Impact of Crowding Thereon: A Combined Neutron Spectroscopy and Molecular Dynamics Simulation S...
Published 2022“…Intrinsically disordered proteins (IDPs) are proteins that, in comparison with globular/structured proteins, lack a distinct tertiary structure. Here, we use the model IDP, Histatin 5, for studying its dynamical properties under self-crowding conditions with quasi-elastic neutron scattering in combination with full atomistic molecular dynamics (MD) simulations. …”
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8737
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8738
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8739
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8740