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9461
Structural Studies of the <i>Methylosinus trichosporium</i> OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel
Published 2020“…The kinetics of reaction of O<sub>2</sub> with the diferrous sMMOH:MMOB complex in solution show that use of the MMOB V41R variant decreases the rate constant for O<sub>2</sub> binding >25000-fold without altering the component affinity. …”
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9462
Nicotinic acetylcholine receptors (nAChRs) are expressed in Trpm5 positive taste receptor cells (TRCs)
Published 2018“…This indicates that nicotine evokes bitter taste by activating a Trpm5-dependent pathway and a Trpm5-independent but nAChR-dependent pathway. …”
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9463
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9464
AUT00201 (1 µM) can rescue AP width in cuprizone mice.
Published 2025“…<p><b>A</b>. Bath application of AUT00201 1 µm decreased the rheobase of PV interneurons from cuprizone mice but not control mice (<i>group x AUT00201 two-way repeated measures: n = 12,13 cells from 4 mice per group: F(1,12) = 0.1816, p = 0.6775; AUT00201 effect: F(1,12) = 7.122, *p = 0.0205. …”
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9465
Heat-stress-induced changes in enzymatic antioxidant activities and biochemical processes in bell pepper (Capsicum annuum L.) seedlings
Published 2023“…At 40 and 32 °C, HS led to a decrease in chlorophyll a (4.327 mg g–1 FW), b (1.710 mg g–1 FW), total chlorophyll (5.202 mg g–1 FW), and total carotene (1.092 mg g–1 FW) compared to the control at 25 °C (chlorophyll a 5.383 mg g–1 FW, chlorophyll b 2.358 mg g–1 FW, total chlorophyll 6.692 mg g–1 FW, and total carotene 1.817 mg g–1 FW). …”
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9466
Image5_A Role of Caveolae in Trabecular Meshwork Mechanosensing and Contractile Tone.JPEG
Published 2022“…Treatment with the Cav1 scaffolding domain mimetic, cavtratin (1 μM) caused a reduction in pMLC (70 ± 5% n = 7, p = 0.001), as did treatment with the scaffolding domain mutant cavnoxin (1 μM) (82 ± 7% n = 7, p = 0.04). …”
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9467
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9468
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9469
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9470
Human AQP5 Plays a Role in the Progression of Chronic Myelogenous Leukemia (CML)
Published 2008“…While normal bone marrow biopsy samples (n = 5) showed no expression of AQP5, 32% of CML patient samples (n = 41) demonstrated AQP5 expression. …”
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9471
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9472
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9473
A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice
Published 2016“…Here, we demonstrate reduced insulin resistance and the anti-obesity effect of a D5D selective inhibitor (compound-326), an orally active small-molecule, in a high-fat diet-induced obese (DIO) mouse model. …”
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9474
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9475
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9476
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9477
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9478
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9479
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9480
Effect of AUT00201 (1 µM) on PV properties after juvenile demyelination.
Published 2025“…<p><b>A-B.</b> Bath application of AUT00201 (1 µM) had no significant effect on the resting membrane potential (A) or the input resistance (B) of PV interneurons from cuprizone mice and control mice (RMP: <i>group x AUT00201 two-way repeated measures: n = 12,13 cells from 4 mice per group: p = 0.8593; AUT00201 effect: p = 0.2171.…”