Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability. by Giorgia Urbinati (554921)

“…<p>VCaP cells were transfected for 72h from 2.5 nM to 50 nM with siRNA TMPRSS2-ERG III, siRNA TMPRSS2-ERG IV or siRNA Control. …”

Vectorized siRNA TMPRSS2-ERG IV-SQ impaired tumour growth and restored differentiation <i>in vivo</i>. by Giorgia Urbinati (554921)

“…<p><b>a.</b> SCID mice (n = 5/group) bearing VCaP tumour xenografts were injected intravenously either with NaCl 0.9%, non-vectorized siRNA TMPRSS2-ERG IV, NPs siRNA control-SQ or NPs siRNA TMPRSS2-ERG IV-SQ twice per week during 6 weeks (1.8 mg/kg/mouse cumulative dose). …”

Cellular co-infection decreases the potential for superinfection. by Brigitte E. Martin (8366847)

Metal-reactive lymphocytes from individuals’ exhibit significant decreased metal-reactivity in the presence of inflammasome based inhibitors. by Lauryn Samelko (424639)

Coibamide A induces a time- and concentration-dependent decrease in plasma membrane integrity. by Andrew M. Hau (418935)

Normal cell death but decreased cell proliferation of in <i>MiR125a</i>^-/- neutrophils. by Yuting Qin (1950118)

Decreased proliferation of immature neutrophils in <i>MiR125a</i>^<i>-/-</i> mice. by Yuting Qin (1950118)

Transfer of RSV-infected <i>Kdm5b</i>-deficient DCs leads to a decreased pathogenic pulmonary RSV challenge. by Catherine Ptaschinski (756139)

The T37A substitution increases both H5N6 M1 protein stability and H5N6 viral replication in mammals. by Chenxi Wang (284364)

Subjects:

Genetic predisposition to elevated levels of C-reactive protein is associated with a decreased risk for preeclampsia by Cassandra N. Spracklen (3131484)

“…<i>Results</i>: The genetic risk score (GRS) related to higher levels of CRP demonstrated a significantly decreased risk of preeclampsia (OR 0.89, 95% CI 0.82–0.96). …”

TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment. by Fiona McDonnell (2636635)

“…A 0hr Control was set to 100%, and the normoxic and hypoxic results were presented as a percentage of this; Normoxic = 95.5%, Hypoxic = 159.4% (P<0.01). n = 3 *P<0.05, **P<0.01. …”

Decreased reductase activity and increased round body formation in the <i>gpsA</i> mutant. by Dan Drecktrah (36180)

(A) Decreasing CaMKII activity by KN-93 (high-3 µmol/L, low-0.5 µmol/L), AIP (high-10 µmol/L, low-2 µmol/L), or decreasing calmodulin activity by W-7 (high-50 µmol/L, low-20 µmol/L) decreases spontaneous AP firing rate (n = 10 for each drug), cAMP (n = 4 for each drug) and ATP (n = 5 for each drug). by Yael Yaniv (162548)

Viability decreases in PRR15-deficient ACH-3P cells. by Katherine C. Gates (3907456)

Targeted point mutation (F639A) in the GluN1 subunit decreases ethanol sensitivity of NMDA receptors. by Carolina R. den Hartog (484817)

Effects of NDGA on the expression of JA synthesis-related genes. by Hiroaki Tamaki (758505)

Sphingomyelinase activity decreases in Alzheimer’s disease. by Alfred N. Fonteh (486638)

Cardamonin decreased the expression of lipogenic proteins. by Peiguang Niu (17044532)

ShakB(N+16) increases, and ShakB(N) decreases, NB coupling. by Sami H. Jezzini (650703)

An enhanced clot growth rate before in vitro fertilization decreases the probability of pregnancy by A. N. Balandina (6729380)