Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. by Xiaowen Jiang (8291814)

Orsay virus infection of the <i>lin-8(n2731</i>) synMuv A mutant induces a Muv phenotype indicative of decreased synMuv B gene activity, and 2 different synMuv B mutants produce 50–100× less Orsay virus RNA. by Ashwin Seetharaman (615458)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

Subjects:

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

Subjects:

Foldases and holdases each decrease the level of unfolded protein. by Adam MR de Graff (9767829)

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…The most active compound is 3-benzoylamino<i>-N</i>-(2-ethyl-phenyl)-benzamide or <b>F3</b>, blocking TASK-1 with an IC₅₀ of 148 nM, showing a reduced inhibition of TASK-3 channels and not a significant effect on different K⁺ channels. …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…The most active compound is 3-benzoylamino<i>-N</i>-(2-ethyl-phenyl)-benzamide or <b>F3</b>, blocking TASK-1 with an IC₅₀ of 148 nM, showing a reduced inhibition of TASK-3 channels and not a significant effect on different K⁺ channels. …”

A typical GABA-MRS spectrum, where peaks of GABA, NAA, and combined glutamate and glutamine (Glx) are measured. by Hiroyuki Matsuta (13250169)

Subjects:

Decrease of autoantibody levels in highly inflammatory NSG mice. by Henrika Jodeleit (4722312)

Decrease in vRNA in brain during antiretroviral therapy. by Sonny R. Elizaldi (9684796)

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

“…In contrast, only a single fast population was measured in [P₆₆₆₁₄][Cl] at 50 °C. …”

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

“…In contrast, only a single fast population was measured in [P₆₆₆₁₄][Cl] at 50 °C. …”

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

“…In contrast, only a single fast population was measured in [P₆₆₆₁₄][Cl] at 50 °C. …”

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

“…In contrast, only a single fast population was measured in [P₆₆₆₁₄][Cl] at 50 °C. …”

K562 cells were treated with 40 nM of miR-214 mimics or a negative mimics control for 24 h, followed by treatment with 50 μM of hemin for 48 h. by Tipparat Penglong (164413)

IL-17A promotes the expression of osteoclast-related genes involved in osteoclastogenesis. by Hao Tang (44155)

<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays. by Ling Tian (107492)

Plot of mean vigor by group and time. by Kunal Desai (18784208)

“…</p><p>Results</p><p>The majority of participants were nurses (50%), followed by allied healthcare professionals (37%) and physicians (13%) (N = 83). …”

Plot of mean Burnout by group and time. by Kunal Desai (18784208)

“…</p><p>Results</p><p>The majority of participants were nurses (50%), followed by allied healthcare professionals (37%) and physicians (13%) (N = 83). …”

IL-17A promotes RANKL-stimulated osteoclastogenesis. by Hao Tang (44155)